Recombinant Human B-cell Maturation Protein (TNFRSF17)
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產(chǎn)品名稱: Recombinant Human B-cell Maturation Protein (TNFRSF17)
產(chǎn)品型號: Z101449
產(chǎn)品展商: 其他品牌
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簡單介紹
Recombinant Human B-cell Maturation Protein (TNFRSF17)
Recombinant Human B-cell Maturation Protein (TNFRSF17)
的詳細(xì)介紹
|
Print Version |
| Alternative Names |
Tumor necrosis factor receptor superfamily member 17, TNFRSF17, B cell maturation antigen, BCM, BCMA, CD269 |
| Description |
BCMA (B cell maturation) is a nonglycosylated integral membrane type I protein that is preferentially expressed in mature B lymphocytes.The N-terminal part of both mouse and human proteins contains a conserved six-cysteine motif. BLyS binds to three receptors of the TNF receptor family (B cell maturation antigen BCMA, TACI, and BAFF-R), all of which are expressed by mature B cells. |
| Gene Symbol |
TNFRSF17 |
| Gene ID |
608 |
| Accession No. |
Q02223 |
| Source |
E. coli |
| Appearance |
Lyophilized Powder |
| Molecular Weight |
6.0 kDa |
| Endotoxin Level |
<1.0 EU/μg of recombinant protein as determined by the LAL method |
| Purity |
>95% as determined by SDS-PAGE |
| Gel Image |
 |
| Bioactivity |
The ED(50) was determined by the dose-dependent proliferation of KMS15 cells and was found to be <0.05ng/mL. |
| Bioactivity Data |
 |
| Formulation |
Lyophilized from a 0.2 μm filtered solution in PBS |
| Reconstitution |
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage |
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage |
For research use only. Not for diagnostic or therapeutic use. |
