Anti-Nerve Growth Factor Receptor produced in mouse Antibody
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產(chǎn)品名稱: Anti-Nerve Growth Factor Receptor produced in mouse Antibody
產(chǎn)品型號: Y062078
產(chǎn)品展商: 其他品牌
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簡單介紹
Anti-Nerve Growth Factor Receptor produced in mouse Antibody
Anti-Nerve Growth Factor Receptor produced in mouse Antibody
的詳細介紹
| Overview |
Print Version
|
| Product Name |
Anti-Nerve Growth Factor Receptor produced in mouse Antibody |
| Description |
Monoclonal Anti-Nerve Growth Factor Receptor antibody produced in mouse clone ME20.4, ascites fluid |
| Subtype |
monoclonal |
| Application |
WB,IHC,Flow Cyt |
| Raised In |
mouse |
| Specificity |
Recognizes the low affinity human NGFR p75 (also known as gp75NGFR , p75NGFR and p75NTR).1 The epitope recognized by the antibody exists within the third or fourth cysteine-rich repeats of the NGFR molecule. May be used in various immunoassays including inhibition of NGF binding to p75-NGFR and as a cholinergic immunotoxin. |
| Immunogen |
human melanoma cell line WM245. |
| Guarantee |
abm guarantees that all our Anti-Nerve Growth Factor Receptor produced in mouse Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Properties |
|
| Formulation |
Liquid |
| Quantity |
100 μl |
| Clone |
ME20.4 |
| Storage |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Storage Buffer |
PBS, pH 7.4 with 0.05% sodium azide. |
| Concentration |
1μg/ul |
| Purity |
ascites fluid |
| Isotype |
IgG1 |
| Species Reactivity |
human,other |
| Specific References |
|
Y062078 has been referenced in 1 publication.
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1. Ross, A.H., et al., Characterization of nerve growth factor receptor in neural crest tumors using monoclonal antibodies. Proc. Natl. Acad. Sci. USA 81, 6681-6685, (1984)Yan, H., and Chao, M.V., Disruption of cysteine-rich repeats of the p75 nerve growth factor receptor leads to loss of ligand binding. J. Biol. Chem. 266, 12099, (1991)Dominici, C., et al., Immunohistochemical detection of p140trkA and p75LNGFR neurotrophin receptors in neuroblastoma. J. Neurooncol. 31, 57-64, (1997) Fine, A., et al., Learning impairments following injection of a selective cholinergic immunotoxin ME20.4 IgG-saporin into the basal nucleus of Meynert in monkeys. Neuroscience 81, 331, (1997) Vissavajjhala, P., Structural domains of the extracellular domain of human nerve growth factor receptor detected by partial proteolysis. Arch. Biochem. Biophys. 294, 244, (1992)
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