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產(chǎn)品名稱: Recombinant Human CCL22
產(chǎn)品型號: Z101019
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關文檔
簡單介紹
Recombinant Human CCL22
Recombinant Human CCL22
的詳細介紹
|
Print Version |
| Alternative Names |
STCP-1, ABCD-1, CCL22, CC chemokine STCP-1, MDC(1-69), SCYA22, Small-inducible cytokine A22, Stimulated T-cell chemotactic protein 1, MDC, C-C motif chemokine 22
Recombinant Human Macrophage-Derived Chemokine (CCL22) |
| Description |
CCL22 (monocyte-derived chemokine) was described initially as a constitutively produced, thymus-specific chemokine, implicated in the recruitment of T cells . One of the functions of CCL22 originally described was induction of migration of CCR4+ Th2 cells, but it has additionally been shown to regulate migration of Tregs. CCL22 has been implicated in a number of diseases, including allergen-induced lung inflammation, atopic dermatitis, and lymphoma. Similarly, a presumed role for CCR4+ cells has been suggested for endotoxic shock, rheumatoid arthritis, T cell lymphoma, and autoimmune diabetes |
| Gene Symbol |
CCL22 |
| Gene ID |
6367 |
| Accession No. |
O00626 |
| Source |
E. coli |
| Appearance |
Lyophilized Powder |
| Molecular Weight |
8.0 kDa |
| Endotoxin Level |
<1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Purity |
>95% as determined by SDS-PAGE |
| Gel Image |
 |
| Bioactivity |
The ED(50) was determined by the dose-dependent proliferation of MGC823 cells and was found to be <5ng/mL. |
| Bioactivity Data |
 |
| Formulation |
Lyophilized from 0.2 μm filtered solution in Tris and NaCl, pH 7.0. |
| Reconstitution |
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage |
Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months.
Avoid repeated freeze/thaw cycles. |
| Usage |
For research use only. Not for diagnostic or therapeutic use. |
