Human Drebrin-like protein (DBNL) ELISA kit; ABP1; HIP-55; SH3P7; src homology 3 domain-containing protein HIP-55; drebrin-like

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of DBNL elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9337628 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the drebrin-like (DBNL) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DBNL. The ELISA analytical biochemical technique of the MBS9337628 kit is based on DBNL antibody-DBNL antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DBNL antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DBNL. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

48,207 Da

drebrin-like

drebrin-like protein; drebrin-F; cervical SH3P7; SH3 domain-containing protein 7; cervical mucin-associated protein; HPK1-interacting protein of 55 kDa; src homology 3 domain-containing protein HIP-55

Drebrin-like protein

CMAP; SH3P7; PP5423; HIP-55??[Similar Products]

DBNL_HUMAN

DBNL: an SH3-containing adaptor protein. Interacts with hematopoietic progenitor kinase 1a (HIPK1). It is recruited to glycolipid-enriched microdomains following T cell receptor (TCR) stimulation. Interacts with and is phosphorylated by ZAP-70 after TCR signaling. May regulate JNK activation following TCR signaling, presumably via its interaction with HIPKIt is a member of the drebrin family of proteins that are developmentally regulated in the brain.

Protein type: Motility/polarity/chemotaxis; Actin-binding

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: Golgi membrane; ruffle; lamellipodium; cytoplasm; postsynaptic density; dendrite; plasma membrane; clathrin coated vesicle membrane; podosome; cell cortex; cytosol; cell junction

Molecular Function: protein C-terminus binding; actin filament binding; protein domain specific binding; protein binding; enzyme activator activity; actin binding

Biological Process: receptor-mediated endocytosis; synaptogenesis; apoptosis; immune system process; Rac protein signal transduction; activation of JNK activity; neurite morphogenesis; cell structure disassembly during apoptosis

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