Product Name
FAM126A, Polyclonal Antibody
Full Product Name
FAM126A antibody - C-terminal region
Product Gene Name
anti-FAM126A antibody
[Similar Products]
Product Synonym Gene Name
DRCTNNB1A; HCC; HLD5; HYCC1[Similar Products]
Antibody/Peptide Pairs
FAM126A peptide (MBS3239654) is used for blocking the activity of FAM126A antibody (MBS3214718)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: MEISEVDEGF YSRAASSTSQ SGLSNSSHNC SNKPSIGKNH RRSGGSKTGG
3D Structure
ModBase 3D Structure for Q9BYI3
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 79%; Dog: 79%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 85%; Rabbit: 86%; Rat: 85%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human FAM126A
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-FAM126A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FAM126A antibody
This is a rabbit polyclonal antibody against FAM126A. It was validated on Western Blot
Target Description: FAM126A may play a part in the beta-catenin/Lef signaling pathway. Expression of FAM126A gene is down-regulated by beta-catenin. Defects in FAM126A gene are a cause of hypomyelination with congenital cataract (HCC).
Product Categories/Family for anti-FAM126A antibody
Polyclonal; Disease Related;
Applications Tested/Suitable for anti-FAM126A antibody
Western Blot (WB)
Western Blot (WB) of anti-FAM126A antibody
WB Suggested Anti-FAM126A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Human Lung
NCBI/Uniprot data below describe general gene information for FAM126A. It may not necessarily be applicable to this product.
NCBI Accession #
NP_115970
[Other Products]
NCBI GenBank Nucleotide #
NM_032581
[Other Products]
UniProt Primary Accession #
Q9BYI3
[Other Products]
UniProt Related Accession #
Q9BYI3[Other Products]
NCBI Official Full Name
hyccin isoform 1
NCBI Official Synonym Full Names
family with sequence similarity 126 member A
NCBI Official Symbol
FAM126A??[Similar Products]
NCBI Official Synonym Symbols
HCC; HLD5; HYCC1; DRCTNNB1A
??[Similar Products]
NCBI Protein Information
hyccin
UniProt Protein Name
Hyccin
UniProt Synonym Protein Names
Down-regulated by CTNNB1 protein A; Protein FAM126A
UniProt Gene Name
FAM126A??[Similar Products]
UniProt Synonym Gene Names
DRCTNNB1A??[Similar Products]
UniProt Entry Name
HYCCI_HUMAN
NCBI Summary for FAM126A
The protein encoded by this gene may play a part in the beta-catenin/Lef signaling pathway. Expression of this gene is down-regulated by beta-catenin. Defects in this gene are a cause of hypomyelination with congenital cataract (HCC). [provided by RefSeq, Oct 2008]
Research Articles on FAM126A
1. point to a role for FAM126A in supporting myelination, an important process in development and also following acute exacerbations in multiple sclerosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
