Product Name
HGD, Blocking Peptide
Full Product Name
HGD Peptide - middle region
Product Gene Name
HGD blocking peptide
[Similar Products]
Product Synonym Gene Name
AKU; HGO[Similar Products]
HGD peptide (MBS3235290) is used for blocking the activity of HGD antibody (MBS3210334)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q93099
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of HGD blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
HGD blocking peptide
This is a synthetic peptide designed for use in combination with anti-HGD antibody made
Target Description: Homogentisate 1,2-dioxygenase (HGD) gene mutations are the molecular cause of alkaptonuria, a rare hereditary disorder of the phenylalanine catabolism. The highest expression of HGD is in the prostate, small intestine, colon, and liver. The HGD gene contains 14 exons. Conflicting reports have placed the gene at 3q2, 3q13.3-q21, 3q21-q24, 3q21-q23, or 3q25-q26.Homogentisate 1,2-dioxygenase (HGD) gene mutations are the molecular cause of alkaptonuria, a rare hereditary disorder of the phenylalanine catabolism. The highest expression of HGD is in the prostate, small intestine, colon, and liver. The HGD gene contains 14 exons. Conflicting reports have placed the gene at 3q2, 3q13.3-q21, 3q21-q24, 3q21-q23, or 3q25-q26. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Product Categories/Family for HGD blocking peptide
Peptide
Applications Tested/Suitable for HGD blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for HGD. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000178
[Other Products]
NCBI GenBank Nucleotide #
NM_000187
[Other Products]
UniProt Primary Accession #
Q93099
[Other Products]
UniProt Related Accession #
Q93099[Other Products]
NCBI Official Full Name
homogentisate 1,2-dioxygenase
NCBI Official Synonym Full Names
homogentisate 1,2-dioxygenase
NCBI Official Symbol
HGD??[Similar Products]
NCBI Official Synonym Symbols
AKU; HGO
??[Similar Products]
NCBI Protein Information
homogentisate 1,2-dioxygenase
UniProt Protein Name
Homogentisate 1,2-dioxygenase
UniProt Synonym Protein Names
Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase
Protein Family
2-(hydroxymethyl)glutarate dehydrogenase
UniProt Gene Name
HGD??[Similar Products]
UniProt Synonym Gene Names
HGO??[Similar Products]
UniProt Entry Name
HGD_HUMAN
NCBI Summary for HGD
This gene encodes the enzyme homogentisate 1,2 dioxygenase. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria.[provided by RefSeq, May 2010]
Research Articles on HGD
1. Twelve novel HGD gene variants have been identified in 99 alkaptonuria patients affecting the bones.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.