Full Product Name
COT2 Antibody
Product Synonym Names
apolipoprotein AI regulatory 1; ARP-1; COT2; COUP transcription factor 2; COUP-TF II; COUP-TF2
Product Gene Name
anti-COT2 antibody
[Similar Products]
Product Synonym Gene Name
NR2F2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P24468
Species Reactivity
Human, Mouse, Rat
Specificity
COT2 Antibody detects endogenous levels of total COT2 protein.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human COT2.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Other Notes
Small volumes of anti-COT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-COT2 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-COT2 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:10000
Immunofluorescence (IF) of anti-COT2 antibody
Immunofluorescence analysis of HUVEC cells, using COT2 Antibody. The picture on the right is blocked with the synthesized peptide.
Western Blot (WB) of anti-COT2 antibody
Western blot analysis of lysates from HUVEC cells, using COT2 Antibody. The lane on the right is blocked with the synthesized peptide.
NCBI/Uniprot data below describe general gene information for COT2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001138627.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001145155.1
[Other Products]
UniProt Primary Accession #
P24468
[Other Products]
UniProt Secondary Accession #
Q03754; Q3KQR7; B4DQJ2; B6ZGU1[Other Products]
UniProt Related Accession #
P24468[Other Products]
NCBI Official Full Name
COUP transcription factor 2 isoform b
NCBI Official Synonym Full Names
nuclear receptor subfamily 2 group F member 2
NCBI Official Symbol
NR2F2??[Similar Products]
NCBI Official Synonym Symbols
ARP1; CHTD4; NF-E3; NR2F1; SVP40; COUPTFB; TFCOUP2; COUPTFII
??[Similar Products]
NCBI Protein Information
COUP transcription factor 2
UniProt Protein Name
COUP transcription factor 2
UniProt Synonym Protein Names
Apolipoprotein A-I regulatory protein 1; ARP-1; COUP transcription factor II; COUP-TF II; Nuclear receptor subfamily 2 group F member 2
UniProt Gene Name
NR2F2??[Similar Products]
UniProt Synonym Gene Names
ARP1; TFCOUP2; COUP-TF2; ARP-1; COUP-TF II??[Similar Products]
NCBI Summary for COT2
This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
UniProt Comments for COT2
Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.
Research Articles on COT2
1. Low COUPTFII expression is associated with prostate cancer.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
