Product Name
TSPAN31, Polyclonal Antibody
Full Product Name
TSPAN31 antibody - middle region
Product Gene Name
anti-TSPAN31 antibody
[Similar Products]
Product Synonym Gene Name
SAS[Similar Products]
Antibody/Peptide Pairs
TSPAN31 peptide (MBS3233245) is used for blocking the activity of TSPAN31 antibody (MBS3208283)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: CTAICKSQSP TCQMCGEKFL KHSDEALKIL GGVGLFFSFT EILGVWLAMR
3D Structure
ModBase 3D Structure for Q12999
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TSPAN31
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-TSPAN31 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TSPAN31 antibody
This is a rabbit polyclonal antibody against TSPAN31. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: TSPAN31 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma.The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma.
Product Categories/Family for anti-TSPAN31 antibody
Polyclonal; Signal Proteins; Membrane Protein; Developmental Biology; Signal Transduction; Membrane & Traffic;
Applications Tested/Suitable for anti-TSPAN31 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Immunohistochemistry (IHC) of anti-TSPAN31 antibody
Rabbit Anti-TSPAN31 Antibody
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Plasma membrane and cytoplasm in hepatocytes
Primary Antibody Concentration: N/A
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

Western Blot (WB) of anti-TSPAN31 antibody
WB Suggested Anti-TSPAN31 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Muscle

NCBI/Uniprot data below describe general gene information for TSPAN31. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005972
[Other Products]
NCBI GenBank Nucleotide #
NM_005981
[Other Products]
UniProt Primary Accession #
Q12999
[Other Products]
UniProt Related Accession #
Q12999[Other Products]
NCBI Official Full Name
tetraspanin-31 isoform 1
NCBI Official Synonym Full Names
tetraspanin 31
NCBI Official Symbol
TSPAN31??[Similar Products]
NCBI Official Synonym Symbols
SAS
??[Similar Products]
NCBI Protein Information
tetraspanin-31
UniProt Protein Name
Tetraspanin-31
UniProt Synonym Protein Names
Sarcoma-amplified sequence
Protein Family
Tetraspanin
UniProt Gene Name
TSPAN31??[Similar Products]
UniProt Synonym Gene Names
SAS??[Similar Products]
UniProt Entry Name
TSN31_HUMAN
NCBI Summary for TSPAN31
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008]
UniProt Comments for TSPAN31
TSPAN31: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008]
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q13.3
Cellular Component: membrane; integral to plasma membrane
Biological Process: positive regulation of cell proliferation
Research Articles on TSPAN31
1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Precautions
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Disclaimer
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