Product Name
Aminoacylase-1 (ACY1), Recombinant Protein
Full Product Name
Recombinant Pig Aminoacylase-1 (ACY1)
Product Gene Name
ACY1 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-407aa, Full Length of Mature Protein
Sequence
ASKGREGEHP SVTLFRQYLR IRTVQPEPDY GAAVAFLEER ARQLGLGCQK VEVVPGHVVT VLTWPGTNPT LSSILLNSHT DVVPVFKEHW SHDPFEGFKD ADGYIYGRGA QDMKCVSIQY LEAVRRLKVE GHHFPRTIHM TFVPDEEVGG HQGMELFVKR PEFQALRAGF ALDEGLASPT DAFTVFYSER SPWWLRVTST GKPGHGSRFI EDTAAEKLHK VINSILAFRE KEKQRLQSNQ LKPGAVTSVN LTMLEGGVAY NVVPATMSAC FDFRVAPDVD LKAFEEQLQS WCQAAGEGVT FEFVQKWMET QVTSTDDSDP WWAAFSGVFK DMKLALELEI CPASTDARYI RAAGVPALGF SPMNHTPVLL HDHDERLHEA VFLRGVDIYT QLLSALASVP ALPSES
3D Structure
ModBase 3D Structure for P37111
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ACY1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ACY1 recombinant protein
Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes.
NCBI/Uniprot data below describe general gene information for ACY1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_999061.1
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NCBI GenBank Nucleotide #
NM_213896.1
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UniProt Primary Accession #
P37111
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UniProt Related Accession #
P37111[Other Products]
Molecular Weight
45,347 Da
NCBI Official Full Name
aminoacylase-1
NCBI Official Symbol
ACY1??[Similar Products]
NCBI Protein Information
aminoacylase-1
UniProt Protein Name
Aminoacylase-1
UniProt Synonym Protein Names
N-acyl-L-amino-acid amidohydrolase
Protein Family
Aminoacylase
UniProt Gene Name
ACY1??[Similar Products]
UniProt Synonym Gene Names
ACY-1??[Similar Products]
UniProt Comments for ACY1
Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate).
Research Articles on ACY1
1. T347S variant of human Acy1 exhibited markedly increased catalytic efficiency against N-benzoylamino acids
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
