Product Name
Glucose Transporter GLUT2, Polyclonal Antibody
Full Product Name
Glucose transporter GLUT2 Antibody FITC-Conjugated
Product Synonym Names
liver; Glucose Transporter 2; Glucose transporter type 2 liver; Glucose transporter, liver/islet; GLUT2; GTT2; SLC2A2; Solute carrier family 2 (facilitated glucose transporter) member 2 antibody
Product Gene Name
anti-GLUT2 antibody
[Similar Products]
Antibody/Peptide Pairs
Glucose Transporter GLUT2 peptide (MBS543764) is used for blocking the activity of Glucose Transporter GLUT2 antibody (MBS541715)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P14246
Species Reactivity
Human, Mouse, Rat
Form/Format
FITC-Conjugated
Concentration
0.5 ug/ul in antibody stabilization buffer (lot specific)
Immunogen
Synthetic peptide taken within amino acid region 1-50 on human GLUT2 protein.
Expression
In embryo, expressed in endoderm layer of yolk sac and liver primordium
Molecular Function
glucose transmembrane transporter activity
Structure
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
Subcellular Location
Membrane
Preparation and Storage
-20? degree C for long term storage
Other Notes
Small volumes of anti-GLUT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GLUT2 antibody
FITC-Conjugated Solute carrier family 2 glucose transporter member 2 Antibody
Facilitative glucose transporter
Applications Tested/Suitable for anti-GLUT2 antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-GLUT2 antibody
Confocal Microscopy||1:100
Dot Blot: 1:8,000
ELISA: 1:8,000
Immunocytochemistry: 1:100
Immunofluorescence: 1:100
Immunohistochemistry: 1:100
Immunoprecipitation: 1:200
Western Blot: 1:500
NCBI/Uniprot data below describe general gene information for GLUT2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_112474.2
[Other Products]
NCBI GenBank Nucleotide #
NM_031197.2
[Other Products]
UniProt Primary Accession #
P14246
[Other Products]
UniProt Secondary Accession #
Q3TNA5; Q9DBA7[Other Products]
UniProt Related Accession #
P14246[Other Products]
Molecular Weight
57,107 Da
NCBI Official Full Name
solute carrier family 2, facilitated glucose transporter member 2
NCBI Official Synonym Full Names
solute carrier family 2 (facilitated glucose transporter), member 2
NCBI Official Symbol
Slc2a2??[Similar Products]
NCBI Official Synonym Symbols
Glut2; Glut-2; AI266973
??[Similar Products]
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 2
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 2
UniProt Synonym Protein Names
Glucose transporter type 2, liver; GLUT-2
UniProt Gene Name
Slc2a2??[Similar Products]
UniProt Synonym Gene Names
Glut-2; Glut2; GLUT-2??[Similar Products]
UniProt Entry Name
GTR2_MOUSE
UniProt Comments for GLUT2
GLUT2: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Present at high levels in the plasma membrane of pancreatic b-cells where it initiates the first step in glucose-stimulated insulin secretion, a glucose metabolism-dependent signaling mechanism. May mediate the bidirectional transfer of glucose across the plasma membrane of hepatocytes. May also participate with the Na( +2)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Required for glucose sensitivity in the hypothalamus and brain stem. Involved in the control of food intake and stimulation of glucose uptake by peripheral tissues.
Protein type: Transporter; Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral
Cellular Component: apical plasma membrane; basolateral plasma membrane; brush border; brush border membrane; cytoplasm; cytosol; endosome; integral to membrane; intercellular junction; membrane; plasma membrane
Molecular Function: D-glucose transmembrane transporter activity; dehydroascorbic acid transporter activity; glucose transmembrane transporter activity; insulin receptor binding; substrate-specific transmembrane transporter activity; transmembrane transporter activity; transporter activity
Biological Process: carbohydrate transport; carbohydrate utilization; glucose transport; transmembrane transport; transport
Research Articles on GLUT2
1. analysis of the different diabetic responses to STZ in two different animal strains, which both have similar initial GLUT2 expressions in beta cells
Precautions
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Disclaimer
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