SLC2A2; SLC2-A2; Solute carrier family 2, facilitated glucose transporter member 2; Glucose transporter type 2, liver

For Research Use Only. Not for use in diagnostic procedures.

> 95%

Freeze-dried powder

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.

Small volumes of GLUT2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Metabolic pathway; Endocrinology; Hepatology

Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)

Predicted Molecular Weight: 37.7kDa
Accurate Molecular Weight: 40kDa

solute carrier family 2 member 2

solute carrier family 2, facilitated glucose transporter member 2

Solute carrier family 2, facilitated glucose transporter member 2

GLUT2; GLUT-2??[Similar Products]

This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

GLUT2: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Present at high levels in the plasma membrane of pancreatic b-cells where it initiates the first step in glucose-stimulated insulin secretion, a glucose metabolism-dependent signaling mechanism. May mediate the bidirectional transfer of glucose across the plasma membrane of hepatocytes. May also participate with the Na( +2)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Required for glucose sensitivity in the hypothalamus and brain stem. Involved in the control of food intake and stimulation of glucose uptake by peripheral tissues.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 3q26.2

Cellular Component: apical plasma membrane; brush border; cytoplasm; integral component of plasma membrane; intercellular junction; membrane; plasma membrane

Molecular Function: D-glucose transmembrane transporter activity; dehydroascorbic acid transmembrane transporter activity; glucose transmembrane transporter activity; hexose transmembrane transporter activity

Biological Process: carbohydrate metabolic process; glucose transmembrane transport; glucose transport; hexose transport; regulation of insulin secretion

Disease: Diabetes Mellitus, Noninsulin-dependent; Fanconi-bickel Syndrome

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.