Full Product Name
Anti-CPN1 Antibody
Product Gene Name
anti-CPN1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P15169
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Immunogen
Recombinant protein of human CPN1
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-CPN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CPN1 antibody
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins.
Applications Tested/Suitable for anti-CPN1 antibody
Western Blot (WB)
Application Notes for anti-CPN1 antibody
WB: 1:500-1:2000
NCBI/Uniprot data below describe general gene information for CPN1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001299.1
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NCBI GenBank Nucleotide #
NM_001308.2
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UniProt Primary Accession #
P15169
[Other Products]
UniProt Secondary Accession #
B1AP59[Other Products]
UniProt Related Accession #
P15169[Other Products]
Molecular Weight
52,286 Da
NCBI Official Full Name
carboxypeptidase N catalytic chain
NCBI Official Synonym Full Names
carboxypeptidase N subunit 1
NCBI Official Symbol
CPN1??[Similar Products]
NCBI Official Synonym Symbols
CPN; SCPN
??[Similar Products]
NCBI Protein Information
carboxypeptidase N catalytic chain
UniProt Protein Name
Carboxypeptidase N catalytic chain
UniProt Synonym Protein Names
Anaphylatoxin inactivator; Arginine carboxypeptidase; Carboxypeptidase N polypeptide 1; Carboxypeptidase N small subunit; Kininase-1; Lysine carboxypeptidase; Plasma carboxypeptidase B; Serum carboxypeptidase N; SCPN
Protein Family
Carboxypeptidase
UniProt Gene Name
CPN1??[Similar Products]
UniProt Synonym Gene Names
ACBP; CPN; SCPN??[Similar Products]
NCBI Summary for CPN1
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008]
UniProt Comments for CPN1
Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
Research Articles on CPN1
1. CPN binds to fibrinogen and is present in a fibrin clot prepared from plasma.
Precautions
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Disclaimer
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