Product Name
Adenylate cyclase type 1 (ADCY1), Recombinant Protein
Full Product Name
Recombinant Bovine Adenylate cyclase type 1 (ADCY1), partial
Product Gene Name
ADCY1 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
798-1134. Partial-length, covers the Guanylate cyclase 2 Domain
Sequence
SCTLALHARQ VDVKLRLDYL WAAQAEEERD DMEKVKLDNK RILFNLLPAH VAQHFLMSNP RNMDLYYQSY SQVGVMFASI PNFNDFYIEL DGNNMGVECL RLLNEIIADF DELMDKDFYK DLEKIKTIGS TYMAAVGLAP TAGTKAKKCI SSHLSTLADF AIEMFDVLDE INYQSYNDFV LRVGINVGPV VAGVIGARRP QYDIWGNTVN VASRMDSTGV QGRIQVTEEV HRLLRRGSYR FVCRGKVSVK GKGEMLTYFL EGRTDGNGSQ TRSLNSERKM YPFGRAGLQT RLAAGHPPVP PAAGLPVGAG PGALQGSGLA PGPPGQHLPP GASGKEA
3D Structure
ModBase 3D Structure for P19754
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Bos taurus (Bovine)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ADCY1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ADCY1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_776654.1
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NCBI GenBank Nucleotide #
NM_174229.2
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UniProt Primary Accession #
P19754
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UniProt Related Accession #
P19754[Other Products]
Molecular Weight
123,979 Da
NCBI Official Full Name
adenylate cyclase type 1
NCBI Official Synonym Full Names
adenylate cyclase 1
NCBI Official Symbol
ADCY1??[Similar Products]
NCBI Official Synonym Symbols
AC1
??[Similar Products]
NCBI Protein Information
adenylate cyclase type 1
UniProt Protein Name
Adenylate cyclase type 1
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1
Protein Family
Adenylate cyclase
UniProt Gene Name
ADCY1??[Similar Products]
UniProt Synonym Gene Names
AC1??[Similar Products]
UniProt Comments for ADCY1
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:2472670, PubMed:2022671. PubMed:19029295). Mediates responses to increased cellular Ca2+/calmodulin levels (PubMed:2022671, PubMed:19029295). May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
