Product Name
Calcitonin (CALCA), Peptide
Full Product Name
Calcitonin (human) (Biotin)
Product Gene Name
CALCA peptide
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 11; NC_000011.9 (14988214..14993879, complement). Location: 11p15.2
3D Structure
ModBase 3D Structure for P01258
Purity/Purification
Highly Purified
~95%. Purified by HPLC.
Form/Format
Supplied as a lyophilized powder.
Sequence (linear)
Biotin-Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-NH2
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of CALCA peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for CALCA peptide
Molecular Biology; MB-Peptides
NCBI/Uniprot data below describe general gene information for CALCA. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001029124.1
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NCBI GenBank Nucleotide #
NM_001033952.2
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UniProt Primary Accession #
P01258
[Other Products]
UniProt Secondary Accession #
Q13935; Q13937; Q52LX7; B7ZL39[Other Products]
UniProt Related Accession #
P01258; P06881[Other Products]
Molecular Weight
15,466 Da[Similar Products]
NCBI Official Full Name
calcitonin isoform CT preproprotein
NCBI Official Synonym Full Names
calcitonin-related polypeptide alpha
NCBI Official Symbol
CALCA??[Similar Products]
NCBI Official Synonym Symbols
CT; KC; CGRP; CALC1; CGRP1; CGRP-I
??[Similar Products]
NCBI Protein Information
calcitonin; calcitonin gene-related peptide 1; katacalcin; calcitonin 1; alpha-type CGRP; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha
UniProt Protein Name
Calcitonin
UniProt Synonym Protein Names
Calcitonin carboxyl-terminal peptide; CCP; PDN-21
Protein Family
Calcitonin
UniProt Gene Name
CALCA??[Similar Products]
UniProt Synonym Gene Names
CALC1; CCP??[Similar Products]
UniProt Entry Name
CALC_HUMAN
NCBI Summary for CALCA
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
UniProt Comments for CALCA
Function: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.Katacalcin is a potent plasma calcium-lowering peptide.
Subcellular location: Secreted.
Sequence similarities: Belongs to the calcitonin family.
Research Articles on CALCA
1. It is concluded that CGRP is a strong proangiogenic growth factor, thereby contributing to bone development and remodeling by promoting angiogenesis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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