Product Name
Anterior Gradient Protein 3 Homolog (AGR3), Recombinant Protein
Full Product Name
Recombinant Human Anterior Gradient Protein 3 Homolog
Product Synonym Names
AGR3 Human; Anterior Gradient Protein 3 Homolog Human Recombinant; Anterior gradient protein 3 homolog; AG-3; AG3; hAG-3; Breast cancer membrane protein 11; AGR3; BCMP11; UNQ642/PRO1272; HAG3; PDIA18
Product Gene Name
AGR3 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMIAIKKE KRPPQTLSRG WGDDITWVQT YEEGLFYAQK SKKPLMVIHH LEDCQYSQAL KKVFAQNEEI QEMAQNKFIM LNLMHETTDK NLSPDGQYVP RIMFVDPSLT VRADIAGRYS NRLYTYEPRD LPLLIENMKK ALRLIQSEL.
3D Structure
ModBase 3D Structure for Q8TD06
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
AGR3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Sterile Filtered colorless solution.
Preparation and Storage
AGR3 Human Recombinant although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.
Other Notes
Small volumes of AGR3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
AGR3 recombinant protein
Description: AGR3 produced in E Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids (22-166 a.a) and having a molecular mass of 19.5kDa.AGR3 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Anterior gradient protein 3 homolog precursor (AGR3) is a secreted cytoplasmic protein that is involved in metastasis induction and p53 tumor suppressor inhibition. AGR3 may function as molecular marker and potential therapeutic target for hormone-responsive breast tumors.
Product Categories/Family for AGR3 recombinant protein
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Anterior Gradient Protein
NCBI/Uniprot data below describe general gene information for AGR3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_789783.1
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NCBI GenBank Nucleotide #
NM_176813.4
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UniProt Primary Accession #
Q8TD06
[Other Products]
UniProt Secondary Accession #
A4D120[Other Products]
UniProt Related Accession #
Q8TD06[Other Products]
Molecular Weight
19,171 Da
NCBI Official Full Name
anterior gradient protein 3 homolog
NCBI Official Synonym Full Names
anterior gradient 3
NCBI Official Symbol
AGR3??[Similar Products]
NCBI Official Synonym Symbols
AG3; AG-3; HAG3; hAG-3; BCMP11; PDIA18
??[Similar Products]
NCBI Protein Information
anterior gradient protein 3 homolog; anterior gradient homolog 3; breast cancer membrane protein 11; protein disulfide isomerase family A, member 18
UniProt Protein Name
Anterior gradient protein 3 homolog
UniProt Synonym Protein Names
Breast cancer membrane protein 11
Protein Family
Anterior gradient protein
UniProt Gene Name
AGR3??[Similar Products]
UniProt Synonym Gene Names
BCMP11; AG-3; AG3; hAG-3??[Similar Products]
UniProt Entry Name
AGR3_HUMAN
UniProt Comments for AGR3
AGR3: Belongs to the AGR family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 7p21.1
Cellular Component: extracellular region
Molecular Function: protein binding
Research Articles on AGR3
1. AGR3 was is predominantly expressed in liver cholangiocytes but not present in liver hepatocytes, making this protain a good marker for differential diagnosis of intrahepatic cholangiocarcinoma
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.