Product Name
AQP5, Polyclonal Antibody
Popular Item
Full Product Name
AQP5 Polyclonal Antibody
Product Gene Name
anti-AQP5 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P55064
Purity/Purification
Affinity purification
Immunogen
A synthetic peptide of human AQP5
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-AQP5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-AQP5 antibody
Polyclonal
Applications Tested/Suitable for anti-AQP5 antibody
Western Blot (WB)
Application Notes for anti-AQP5 antibody
WB: 1:500 - 1:2000, IHC: 1:50 - 1:100
Western Blot (WB) of anti-AQP5 antibody
Western blot analysis of extracts of mouse liver, using AQP5 Antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
Immunohistochemistry (IHC) of anti-AQP5 antibody
Immunohistochemistry of paraffin-embedded human liver injury using AQP5 antibody (40x lens).
NCBI/Uniprot data below describe general gene information for AQP5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001642.1
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NCBI GenBank Nucleotide #
NM_001651.3
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UniProt Primary Accession #
P55064
[Other Products]
UniProt Secondary Accession #
Q6FGW8[Other Products]
UniProt Related Accession #
P55064[Other Products]
Molecular Weight
Calculated MW: 28kDa
Molecular Weight: 265
NCBI Official Full Name
aquaporin-5
NCBI Official Synonym Full Names
aquaporin 5
NCBI Official Symbol
AQP5??[Similar Products]
NCBI Official Synonym Symbols
PPKB; AQP-5
??[Similar Products]
NCBI Protein Information
aquaporin-5
UniProt Protein Name
Aquaporin-5
UniProt Gene Name
AQP5??[Similar Products]
UniProt Synonym Gene Names
AQP-5??[Similar Products]
UniProt Entry Name
AQP5_HUMAN
NCBI Summary for AQP5
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
UniProt Comments for AQP5
AQP5: Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein type: Membrane protein, integral; Transporter, aquaporin family; Channel, misc.; Membrane protein, multi-pass; Transporter
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: apical plasma membrane; basal plasma membrane; endoplasmic reticulum; integral to plasma membrane; microvillus; plasma membrane
Molecular Function: glycerol channel activity; protein binding; water channel activity
Biological Process: camera-type eye morphogenesis; carbon dioxide transport; excretion; glycerol transport; odontogenesis; pancreatic juice secretion; saliva secretion; transmembrane transport; water transport
Research Articles on AQP5
1. AQP5 defined a subset of patients with Bcl-2-negative and p16-negative tumours with a poor clinical outcome.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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