Product Name
AQP5, Blocking Peptide
Product Synonym Names
Aquaporin-5; AQP-5; AQP5
Product Gene Name
AQP5 blocking peptide
[Similar Products]
Antibody/Peptide Pairs
AQP5 peptide (MBS9219010) is used for blocking the activity of AQP5 antibody (MBS9202904)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P55064
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Membrane; Multi-pass membrane protein.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of AQP5 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
AQP5 blocking peptide
Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.
NCBI/Uniprot data below describe general gene information for AQP5. It may not necessarily be applicable to this product.
NCBI Accession #
P55064.1
[Other Products]
UniProt Primary Accession #
P55064
[Other Products]
UniProt Secondary Accession #
Q6FGW8[Other Products]
UniProt Related Accession #
P55064[Other Products]
Molecular Weight
28,292 Da
NCBI Official Full Name
Aquaporin-5
NCBI Official Synonym Full Names
aquaporin 5
NCBI Official Symbol
AQP5??[Similar Products]
NCBI Official Synonym Symbols
PPKB; AQP-5
??[Similar Products]
NCBI Protein Information
aquaporin-5
UniProt Protein Name
Aquaporin-5
UniProt Gene Name
AQP5??[Similar Products]
UniProt Synonym Gene Names
AQP-5??[Similar Products]
UniProt Entry Name
AQP5_HUMAN
NCBI Summary for AQP5
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
UniProt Comments for AQP5
AQP5: Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein type: Transporter, aquaporin family; Transporter; Membrane protein, multi-pass; Channel, misc.; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: apical plasma membrane; integral to plasma membrane; plasma membrane
Molecular Function: glycerol channel activity; protein binding; water channel activity
Biological Process: carbon dioxide transport; cellular water homeostasis; excretion; odontogenesis; pancreatic juice secretion; water transport
Research Articles on AQP5
1. AQP5 plasma membrane abundance in transfected HEK293 cells is rapidly and reversibly regulated by at least three independent mechanisms involving phosphorylation at Ser156, protein kinase A activity and extracellular tonicity.
Precautions
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Disclaimer
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