Product Name
AG3 / AGR3, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone AGR3.1] (IgG1) to Human AG3 / AGR3
Product Synonym Names
Anti-AG3 / AGR3 Antibody (clone AGR3.1) IHC-plus; AGR3; Anterior gradient homolog 3; BCMP11; AG-3; HAG3; PDIA18; HAG-3; Human AG3; AGR3
Product Gene Name
anti-AG3 antibody
[Similar Products]
Product Synonym Gene Name
AGR3[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8TD06
Specificity
The antibody AGR3.1 recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kD); a secreted cytoplasmic protein which can serve as a marker of carcinogenesis.
Purity/Purification
Protein A Purified
Form/Format
15 mM sodium azide, 0.2% BSA, PBS
Immunogen Description
Purified human AGR3 protein.
Immunogen
AG3 / AGR3 antibody was raised against purified human AGR3 protein.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Other Notes
Small volumes of anti-AG3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-AG3 antibody
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Immunocytochemistry (ICC), Western Blot (WB)
Application Notes for anti-AG3 antibody
ICC, IHC-Fr (1 ug/ml), IHC-P (10 ug/ml), WB (1 ug/ml)
Usage: Western Blotting. Recommended dilution: 1 ug/ml. Positive control: T47D breast cancer cell line. Negative control: H1299 lung carcinoma cell line. Immunohistochemistry (paraffin sections). Recommended dilution: 1 ug/ml. Positive tissue: breast cancer...
Immunohistochemistry (IHC) of anti-AG3 antibody
Anti-AGR3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
NCBI/Uniprot data below describe general gene information for AG3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_789783.1
[Other Products]
NCBI GenBank Nucleotide #
NM_176813.4
[Other Products]
UniProt Primary Accession #
Q8TD06
[Other Products]
UniProt Secondary Accession #
A4D120[Other Products]
UniProt Related Accession #
Q8TD06[Other Products]
Molecular Weight
19,171 Da
NCBI Official Full Name
anterior gradient protein 3 homolog
NCBI Official Synonym Full Names
anterior gradient 3
NCBI Official Symbol
AGR3??[Similar Products]
NCBI Official Synonym Symbols
AG3; AG-3; HAG3; hAG-3; BCMP11; PDIA18
??[Similar Products]
NCBI Protein Information
anterior gradient protein 3 homolog; anterior gradient homolog 3; breast cancer membrane protein 11; protein disulfide isomerase family A, member 18
UniProt Protein Name
Anterior gradient protein 3 homolog
UniProt Synonym Protein Names
Breast cancer membrane protein 11
Protein Family
Pinene synthase
UniProt Gene Name
AGR3??[Similar Products]
UniProt Synonym Gene Names
BCMP11; AG-3; AG3; hAG-3??[Similar Products]
UniProt Entry Name
AGR3_HUMAN
UniProt Comments for AG3
AGR3: Belongs to the AGR family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 7p21.1
Cellular Component: extracellular region
Molecular Function: protein binding
Research Articles on AG3
1. AGR3 was is predominantly expressed in liver cholangiocytes but not present in liver hepatocytes, making this protain a good marker for differential diagnosis of intrahepatic cholangiocarcinoma
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
