Full Product Name
AQP1 Polyclonal Antibody
Product Synonym Names
AQP-CHIP; CHIP28; CO
Product Gene Name
anti-AQP1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P29972
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human AQP1
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-AQP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AQP1 antibody
This gene encodes a small integral membrane protein with six bilayer spanning domains that functions as a water channel protein. This protein permits passive transport of water along an osmotic gradient. This gene is a possible candidate for disorders involving imbalance in ocular fluid movement.
Product Categories/Family for anti-AQP1 antibody
Primary antibody
Applications Tested/Suitable for anti-AQP1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-AQP1 antibody
WB: 1:500 - 1:2000
IHC: 1:50- 1:100
Western Blot (WB) of anti-AQP1 antibody
Western blot analysis of extracts of human normal kidney, using AQP1 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
NCBI/Uniprot data below describe general gene information for AQP1. It may not necessarily be applicable to this product.
NCBI Accession #
P29972.3
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UniProt Primary Accession #
P29972
[Other Products]
UniProt Secondary Accession #
Q8TBI5; Q8TDC1; B5BU39; E7EM69; E9PC21; F5GY19[Other Products]
UniProt Related Accession #
P29972[Other Products]
NCBI Official Full Name
Aquaporin-1
NCBI Official Synonym Full Names
aquaporin 1 (Colton blood group)
NCBI Official Symbol
AQP1??[Similar Products]
NCBI Official Synonym Symbols
CO; CHIP28; AQP-CHIP
??[Similar Products]
NCBI Protein Information
aquaporin-1
UniProt Protein Name
Aquaporin-1
UniProt Synonym Protein Names
Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule
UniProt Gene Name
AQP1??[Similar Products]
UniProt Synonym Gene Names
CHIP28; AQP-1??[Similar Products]
NCBI Summary for AQP1
This gene encodes a small integral membrane protein with six bilayer spanning domains that functions as a water channel protein. This protein permits passive transport of water along an osmotic gradient. This gene is a possible candidate for disorders involving imbalance in ocular fluid movement. [provided by RefSeq, Aug 2016]
UniProt Comments for AQP1
AQP1: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, aquaporin family
Chromosomal Location of Human Ortholog: 7p14.3
Cellular Component: apical part of cell; apical plasma membrane; basal plasma membrane; basolateral plasma membrane; brush border; brush border membrane; cytoplasm; integral to plasma membrane; nuclear membrane; nucleus; plasma membrane; sarcolemma
Molecular Function: ammonium transmembrane transporter activity; glycerol transmembrane transporter activity; intracellular cGMP activated cation channel activity; nitric oxide transporter activity; potassium channel activity; potassium ion transmembrane transporter activity; protein binding; transmembrane transporter activity; water channel activity; water transporter activity
Biological Process: ammonium transport; bicarbonate transport; carbon dioxide transport; cell volume homeostasis; cellular homeostasis; cellular response to stress; cerebrospinal fluid secretion; cGMP biosynthetic process; establishment and/or maintenance of actin cytoskeleton polarity; glycerol transport; lateral ventricle development; multicellular organismal water homeostasis; negative regulation of apoptosis; negative regulation of caspase activity; nitric oxide transport; odontogenesis; pancreatic juice secretion; positive regulation of angiogenesis; positive regulation of fibroblast proliferation; positive regulation of saliva secretion; potassium ion transport; renal water homeostasis; renal water transport; response to drug; water transport
Disease: Blood Group--colton
Research Articles on AQP1
1. data suggest an important functional role of AQP1 in the patho
biology of hypoxia-induced pulmonary hypertension
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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