Full Product Name
TCN1, CT (TCN1, TC1, Transcobalamin-1, Transcobalamin I)
Product Synonym Names
Anti -TCN1, CT (TCN1, TC1, Transcobalamin-1, Transcobalamin I)
Product Gene Name
anti-TCN1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 11; NC_000011.9 (59620281..59634041, complement). Location: 11q11-q12
3D Structure
ModBase 3D Structure for P20061
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Immunogen
TCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-433 amino acids from the C-terminal region of human TCN1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-TCN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TCN1 antibody
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells. [provided by RefSeq].
Product Categories/Family for anti-TCN1 antibody
Antibodies; Abs to Proteins
Applications Tested/Suitable for anti-TCN1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-TCN1 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
NCBI/Uniprot data below describe general gene information for TCN1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001053.2
[Other Products]
NCBI GenBank Nucleotide #
NM_001062.3
[Other Products]
UniProt Primary Accession #
P20061
[Other Products]
UniProt Secondary Accession #
Q8WV77; A8KAC5[Other Products]
UniProt Related Accession #
P20061[Other Products]
Molecular Weight
48,207 Da[Similar Products]
NCBI Official Full Name
transcobalamin-1
NCBI Official Synonym Full Names
transcobalamin I (vitamin B12 binding protein, R binder family)
NCBI Official Symbol
TCN1??[Similar Products]
NCBI Official Synonym Symbols
TC1; TCI; TC-1
??[Similar Products]
NCBI Protein Information
transcobalamin-1; haptocorin; haptocorrin
UniProt Protein Name
Transcobalamin-1
UniProt Synonym Protein Names
Transcobalamin I
Protein Family
Transcobalamin
UniProt Gene Name
TCN1??[Similar Products]
UniProt Synonym Gene Names
TC1; TC-1; TC I; TCI??[Similar Products]
UniProt Entry Name
TCO1_HUMAN
NCBI Summary for TCN1
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells. [provided by RefSeq, Jul 2008]
UniProt Comments for TCN1
TCN1: Vitamin B12-binding protein. Transports cobalamin into cells. Belongs to the eukaryotic cobalamin transport proteins family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11q11-q12
Cellular Component: extracellular space; extracellular region
Molecular Function: cobalamin binding
Biological Process: vitamin metabolic process; cobalamin metabolic process; cobalamin transport; cobalt ion transport; water-soluble vitamin metabolic process
Research Articles on TCN1
1. comparison of human and rainbow trout cobalamin-binding protein
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
