Full Product Name
TCN1 antibody
Product Synonym Names
HC; TC1; TCI; TC-1
Product Gene Name
anti-TCN1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P20061
Specificity
The antibody detects endogenous level of total TCN1 antibody.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (lot specific)
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human TCN1.
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-TCN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TCN1 antibody
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.
Product Categories/Family for anti-TCN1 antibody
Total protein Ab
Applications Tested/Suitable for anti-TCN1 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-TCN1 antibody
Western blotting: 1:500 - 1:2000
Immunofluorescence: 1:50 - 1:200
Western Blot (WB) of anti-TCN1 antibody
Western blot analysis of extracts of various cell lines, using TCN1 antibody.

Immunofluorescence (IF) of anti-TCN1 antibody
Immunofluorescence analysis of U2OS cell using TCN1 antibody. Blue: DAPI for nuclear staining.

NCBI/Uniprot data below describe general gene information for TCN1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001053.2
[Other Products]
NCBI GenBank Nucleotide #
NM_001062.3
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UniProt Primary Accession #
P20061
[Other Products]
UniProt Secondary Accession #
Q8WV77; A8KAC5[Other Products]
UniProt Related Accession #
P20061[Other Products]
Molecular Weight
48,207 Da
NCBI Official Full Name
transcobalamin-1
NCBI Official Synonym Full Names
transcobalamin I (vitamin B12 binding protein, R binder family)
NCBI Official Symbol
TCN1??[Similar Products]
NCBI Official Synonym Symbols
HC; TC1; TCI; TC-1
??[Similar Products]
NCBI Protein Information
transcobalamin-1
UniProt Protein Name
Transcobalamin-1
UniProt Synonym Protein Names
Haptocorrin; HC; Protein R; Transcobalamin I; TC I; TCI
Protein Family
Transcobalamin
UniProt Gene Name
TCN1??[Similar Products]
UniProt Synonym Gene Names
TC1; TC-1; HC; TC I; TCI??[Similar Products]
UniProt Entry Name
TCO1_HUMAN
NCBI Summary for TCN1
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells. [provided by RefSeq, Jul 2008]
UniProt Comments for TCN1
TCN1: Vitamin B12-binding protein. Transports cobalamin into cells. Belongs to the eukaryotic cobalamin transport proteins family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11q11-q12
Cellular Component: extracellular space; extracellular region
Molecular Function: cobalamin binding
Biological Process: vitamin metabolic process; cobalamin metabolic process; cobalamin transport; cobalt ion transport; water-soluble vitamin metabolic process
Research Articles on TCN1
1. Transcobalamins
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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