HC; TC1; TCI; TC-1

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

The antibody detects endogenous level of total TCN1 antibody.

Antibodies were purified by affinity purification using immunogen.

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

1.0 mg/ml (lot specific)

Store at -20 degree C

Small volumes of anti-TCN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.

Total protein Ab

Western Blot (WB), Immunofluorescence (IF)

Western blotting: 1:500 - 1:2000
Immunofluorescence: 1:50 - 1:200

Western blot analysis of extracts of various cell lines, using TCN1 antibody.

Immunofluorescence analysis of U2OS cell using TCN1 antibody. Blue: DAPI for nuclear staining.

48,207 Da

transcobalamin I (vitamin B12 binding protein, R binder family)

transcobalamin-1

Transcobalamin-1

TC1; TC-1; HC; TC I; TCI??[Similar Products]

TCO1_HUMAN

This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells. [provided by RefSeq, Jul 2008]

TCN1: Vitamin B12-binding protein. Transports cobalamin into cells. Belongs to the eukaryotic cobalamin transport proteins family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q11-q12

Cellular Component: extracellular space; extracellular region

Molecular Function: cobalamin binding

Biological Process: vitamin metabolic process; cobalamin metabolic process; cobalamin transport; cobalt ion transport; water-soluble vitamin metabolic process

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