Full Product Name
Anti-TCN1 Antibody
Product Gene Name
anti-TCN1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P20061
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Immunogen
Recombinant protein of human TCN1
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-TCN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TCN1 antibody
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions.
Applications Tested/Suitable for anti-TCN1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TCN1 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:10-1:100
NCBI/Uniprot data below describe general gene information for TCN1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001053.2
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NCBI GenBank Nucleotide #
NM_001062.3
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UniProt Primary Accession #
P20061
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UniProt Secondary Accession #
Q8WV77; A8KAC5[Other Products]
UniProt Related Accession #
P20061[Other Products]
Molecular Weight
48,207 Da
NCBI Official Full Name
transcobalamin-1
NCBI Official Synonym Full Names
transcobalamin 1
NCBI Official Symbol
TCN1??[Similar Products]
NCBI Official Synonym Symbols
HC; TC1; TCI; TC-1
??[Similar Products]
NCBI Protein Information
transcobalamin-1
UniProt Protein Name
Transcobalamin-1
UniProt Synonym Protein Names
Haptocorrin; HC; Protein R; Transcobalamin I; TC I; TCI
Protein Family
Transcobalamin
UniProt Gene Name
TCN1??[Similar Products]
UniProt Synonym Gene Names
TC1; TC-1; HC; TC I; TCI??[Similar Products]
NCBI Summary for TCN1
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells. [provided by RefSeq, Jul 2008]
UniProt Comments for TCN1
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
Research Articles on TCN1
1. Higher placental TC protein abundance was associated with higher cord blood vitamin B12 concentrations, suggesting a potential role in vitamin B12 transport to the fetus.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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