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RPGRIP1L, Antibody

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產(chǎn)品名稱: RPGRIP1L, Antibody
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RPGRIP1L, Antibody


RPGRIP1L, Antibody  的詳細(xì)介紹
Product Name

RPGRIP1L, Antibody

Full Product Name

RPGRIP1L Antibody

Product Gene Name

anti-RPGRIP1L antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
216360
3D Structure
ModBase 3D Structure for Q68CZ1
Other Notes
Small volumes of anti-RPGRIP1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for RPGRIP1L. It may not necessarily be applicable to this product.
NCBI GI #
189217904
NCBI GeneID
23322
NCBI Accession #
NP_001121369.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001127897.3 [Other Products]
UniProt Primary Accession #
Q68CZ1 [Other Products]
UniProt Secondary Accession #
Q9Y2K8; A0PJ88[Other Products]
UniProt Related Accession #
Q68CZ1[Other Products]
Molecular Weight
142,792 Da
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NCBI Official Full Name
protein fantom isoform b
NCBI Official Synonym Full Names
RPGRIP1 like
NCBI Official Symbol
RPGRIP1L??[Similar Products]
NCBI Official Synonym Symbols
FTM; MKS5; CORS3; JBTS7; NPHP8; PPP1R134
??[Similar Products]
NCBI Protein Information
protein fantom
UniProt Protein Name
Protein fantom
UniProt Synonym Protein Names
Nephrocystin-8; RPGR-interacting protein 1-like protein; RPGRIP1-like protein
UniProt Gene Name
RPGRIP1L??[Similar Products]
UniProt Synonym Gene Names
FTM; KIAA1005; NPHP8; RPGRIP1-like protein??[Similar Products]
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NCBI Summary for RPGRIP1L
The protein encoded by this gene can localize to the basal body-centrosome complex or to primary cilia and centrosomes in ciliated cells. The encoded protein has been found to interact with nephrocystin-4. Defects in this gene are a cause of Joubert syndrome type 7 (JBTS7) and Meckel syndrome type 5 (MKS5). [provided by RefSeq, Jun 2016]
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UniProt Comments for RPGRIP1L
Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R) (PubMed:19464661). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis (). Involved in the organization of apical junctions; the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis (PubMed:19464661). Involved in establishment of planar cell polarity such as in cochlear sensory epithelium and is proposed to implicate stabilization of disheveled proteins (). Involved in regulation of proteasomal activity at the primary cilium probably implicating association with PSDM2 ().
Research Articles on RPGRIP1L
1. Importantly, one Japanese and one Omani families carried compound biallelic mutations in two distinct genes (TMEM67/RPGRIP1L and TMEM138/BBS1, respectively).
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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