Product Name
Bardet-Biedl syndrome 12 protein homolog (Bbs12), Recombinant Protein
Full Product Name
Recombinant Mouse Bardet-Biedl syndrome 12 protein homolog (Bbs12)
Product Gene Name
Bbs12 recombinant protein
[Similar Products]
Product Synonym Gene Name
Bbs12[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-708aa, full length protein
Sequence
MEMACRVINR RRHVGLQQLL SFAQTGRSFL GPVKATKFIT DAECHESVLI SSTVRLLEGL DLTCAVGHLL NEAVQAQNNT YKIGTSTLLF LVGAWSRAVE DCLHLGIPTT VIVSVMSEGL NSCIEAVVSL QVPIHNVFDH MDNTSTVYKL ETVNATLCPF LQDPSGSGLL QEKRDFKDAT SPLLSTYSLS GRHAESPKFF KPQNNLETEK NTLQVLKNNL YTDSFCKKSA LAHSRHFNRT DNSHWISRHD GFLEQLESTP KVLRCNDFGE LAVGLSHGDH SSMALAKAAV RLQWQSLCLQ QANWMAPFMF DISRLLTCCI PGLPETFSRV GLGYVTFVTM SSITLIKELQ DQPFRVILIE GDLTESYRHL GFNKSVNIKT KLDSGELSED SAEELWTNHV LQVLIQFNVT LILVQGSVSE HLTEKCMHSK RLVIGAVNGS VLQAFAEATR AVPVAYVTQV NEDCVGSGVS VTFWMSPHDI NRSNRIAILL TAEGINLITA VLTSPASAQM ETKEDRFWSC VYRLYHALKE EKVFLGGGAV EFLCLSHLQI LAEQSLNRGN HACLGWLPDS SSWMASSLSV YRPTVLKSLA GGWHEFLSAI MCNTATHPSA VEARTFIQQH VQNAIDSGSP SSYILSEYSK LSSGVFHSGI SDNLELVPRV YDTVTPKIEA WRRALDVVLL VLQTDSEIIT GLVHTEMNSQ ELDGVLFL
3D Structure
ModBase 3D Structure for Q5SUD9
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Bbs12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Bbs12. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001008502.2
[Other Products]
NCBI GenBank Nucleotide #
NM_001008502.2
[Other Products]
UniProt Primary Accession #
Q5SUD9
[Other Products]
UniProt Secondary Accession #
A2AGT2[Other Products]
UniProt Related Accession #
Q5SUD9[Other Products]
Molecular Weight
78,335 Da
NCBI Official Full Name
Bardet-Biedl syndrome 12 protein homolog isoform 1
NCBI Official Synonym Full Names
Bardet-Biedl syndrome 12 (human)
NCBI Official Symbol
Bbs12??[Similar Products]
NCBI Official Synonym Symbols
Gm407; Gm721; Gm1805
??[Similar Products]
NCBI Protein Information
Bardet-Biedl syndrome 12 protein homolog
UniProt Protein Name
Bardet-Biedl syndrome 12 protein homolog
Protein Family
Bardet-Biedl syndrome 12 protein
UniProt Gene Name
Bbs12??[Similar Products]
UniProt Synonym Gene Names
Gm1805??[Similar Products]
UniProt Comments for Bbs12
Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation ().
Research Articles on Bbs12
1. Despite increased obesity, glucose tolerance was increased with specific enhanced insulin sensitivity in the adipocytes of Bbs12 knockout mice.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.