Product Name
solute carrier family 8 (sodium/calcium exchanger) , member 1 (SLC8A1), ELISA Kit
Full Product Name
Rat Sodium/calcium exchanger 1, SLC8A1 ELISA Kit
Product Synonym Names
Rat Sodium/calcium exchanger 1 (SLC8A1) ELISA kit; DKFZp779F0871; FLJ37694; FLJ43417; MGC119581; NCX1; Na+/Ca++ exchanger; Na+/Ca2+ exchanger; OTTHUMP00000128378; OTTHUMP00000201569; OTTHUMP00000201570; OTTHUMP00000201587; OTTHUMP00000201589; solute carrier family 8 (sodium/calcium exchanger); member 1
Product Gene Name
SLC8A1 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q01728
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of SLC8A1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for SLC8A1 purchase
MBS9341491 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the solute carrier family 8 (sodium/calcium exchanger), member 1 (SLC8A1) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SLC8A1. The ELISA analytical biochemical technique of the MBS9341491 kit is based on SLC8A1 antibody-SLC8A1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLC8A1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLC8A1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for SLC8A1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001257701.1
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NCBI GenBank Nucleotide #
NM_001270772.1
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UniProt Primary Accession #
Q01728
[Other Products]
UniProt Secondary Accession #
Q924Y2; Q9QW49; Q9R238; Q9R239; Q9WU29; Q9WU30[Other Products]
UniProt Related Accession #
Q01728[Other Products]
Molecular Weight
108,185 Da
NCBI Official Full Name
sodium/calcium exchanger 1 isoform 2
NCBI Official Synonym Full Names
solute carrier family 8 (sodium/calcium exchanger), member 1
NCBI Official Symbol
Slc8a1??[Similar Products]
NCBI Official Synonym Symbols
Ncx; Ncx1
??[Similar Products]
NCBI Protein Information
sodium/calcium exchanger 1; Na-Ca exchanger; Na(+)/Ca(2+)-exchange protein 1; solute carrier family 8, member 1
UniProt Protein Name
Sodium/calcium exchanger 1
UniProt Synonym Protein Names
Na(+)/Ca(2+)-exchange protein 1; Solute carrier family 8 member 1
Protein Family
Sodium/calcium exchanger
UniProt Gene Name
Slc8a1??[Similar Products]
UniProt Synonym Gene Names
Ncx1??[Similar Products]
UniProt Entry Name
NAC1_RAT
NCBI Summary for SLC8A1
displays Na+ gradient-dependent Ca2+ transport activity; plays a role in regulation of calcium ion transport [RGD, Feb 2006]
UniProt Comments for SLC8A1
NCX1: Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores. Belongs to the sodium/potassium/calcium exchanger family. SLC8 subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter
Cellular Component: microtubule; mitochondrion; cell; basolateral plasma membrane; integral to plasma membrane; T-tubule; integral to membrane; dendritic spine; cytosol; Z disc; cell projection; membrane; plasma membrane; dendritic shaft; intracellular; sarcolemma
Molecular Function: calmodulin binding; protein binding; metal ion binding; cytoskeletal protein binding; ankyrin binding; calcium:sodium antiporter activity
Biological Process: heart morphogenesis; embryonic placenta development; sodium ion transport; vascular smooth muscle contraction; post-embryonic development; calcium ion homeostasis; elevation of cytosolic calcium ion concentration; cardiac muscle cell development; calcium ion transport; response to glucose stimulus; cell communication; muscle fiber development; regulation of the force of heart contraction; response to nutrient; cardiac muscle contraction; response to drug; cellular sodium ion homeostasis; regulation of heart rate; regulation of sodium ion transport; regulation of calcium ion transport; response to ATP; cellular calcium ion homeostasis; telencephalon development; response to hydrogen peroxide; reduction of cytosolic calcium ion concentration; response to hypoxia; embryonic heart tube development
Research Articles on SLC8A1
1. CRMP2 interacts with NCX and NMDAR and TAT-CBD3 protects against glutamate-induced Ca(2+) dysregulation most likely via suppression of both NMDAR and NCX activities
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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