Product Name
17beta-HSD11, Polyclonal Antibody
Full Product Name
17beta-HSD11 Polyclonal Antibody
Product Gene Name
anti-17beta-HSD11 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8NBQ5
Other Notes
Small volumes of anti-17beta-HSD11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for 17beta-HSD11. It may not necessarily be applicable to this product.
NCBI Accession #
NP_057329.3
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NCBI GenBank Nucleotide #
NM_016245.4
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UniProt Primary Accession #
Q8NBQ5
[Other Products]
UniProt Secondary Accession #
Q96HF6; Q9UKU4[Other Products]
UniProt Related Accession #
Q8NBQ5[Other Products]
Molecular Weight
32,936 Da
NCBI Official Full Name
estradiol 17-beta-dehydrogenase 11
NCBI Official Synonym Full Names
hydroxysteroid 17-beta dehydrogenase 11
NCBI Official Symbol
HSD17B11??[Similar Products]
NCBI Official Synonym Symbols
DHRS8; PAN1B; RETSDR2; SDR16C2; 17BHSD11; 17-BETA-HSD11; 17-BETA-HSDXI
??[Similar Products]
NCBI Protein Information
estradiol 17-beta-dehydrogenase 11
UniProt Protein Name
Estradiol 17-beta-dehydrogenase 11
UniProt Synonym Protein Names
17-beta-hydroxysteroid dehydrogenase 11; 17-beta-HSD 11; 17bHSD11; 17betaHSD11; 17-beta-hydroxysteroid dehydrogenase XI; 17-beta-HSD XI; 17betaHSDXI; Cutaneous T-cell lymphoma-associated antigen HD-CL-03; CTCL-associated antigen HD-CL-03; Dehydrogenase/reductase SDR family member 8; Retinal short-chain dehydrogenase/reductase 2; retSDR2; Short chain dehydrogenase/reductase family 16C member 2
UniProt Gene Name
HSD17B11??[Similar Products]
UniProt Synonym Gene Names
DHRS8; PAN1B; SDR16C2; 17-beta-HSD 11; 17bHSD11; 17betaHSD11; 17-beta-HSD XI; 17betaHSDXI; CTCL-associated antigen HD-CL-03; retSDR2??[Similar Products]
NCBI Summary for 17beta-HSD11
Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009]
UniProt Comments for 17beta-HSD11
Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
Research Articles on 17beta-HSD11
1. knowledge of its in vitro activity together with a newly described expression pattern at the protein level in tissues involved in steroidogenesis and detoxification could suggest a potential role of DHRS8 in vivo
Precautions
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Disclaimer
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