Product Name
Keratin 1 (KRT1), Antibody Pair Kit
Full Product Name
Keratin 1 (KRT1) Antibody Pair Kit (with Standard)
Product Synonym Names
CK1; EHK1; K1; KRT1A; KRT1-A; Cytokeratin 1; Epidermolytic Hyperkeratosis; Keratin, type II cytoskeletal 1; 67 kDa cytokeratin; Type-II keratin Kb1
Product Gene Name
KRT1 antibody pair kit
[Similar Products]
Matching Pairs
Antibody: Keratin 1 (KRT1) (MBS2099014)
Pairing: Keratin 1 (KRT1) (MBS2099014)
Comments: Matched antibody pair kit containing antibody/standard combination
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
Samples
Serum, Plasma, Tissue Homogenates and Other Biological Fluids
Detection Range
0.312-20ng/mL
Standard
Recombinant KRT1 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of KRT1 antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for KRT1 antibody pair kit
Tumor immunity; Developmental science
Applications Tested/Suitable for KRT1 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
NCBI/Uniprot data below describe general gene information for KRT1. It may not necessarily be applicable to this product.
NCBI Accession #
AAB47721.1
[Other Products]
UniProt Secondary Accession #
P85925; P86104; Q14720; Q6GSJ0; Q9H298; B2RA01[Other Products]
UniProt Related Accession #
P04264[Other Products]
Molecular Weight
66,039 Da
NCBI Official Full Name
keratin 1
NCBI Official Synonym Full Names
keratin 1
NCBI Official Symbol
KRT1??[Similar Products]
NCBI Official Synonym Symbols
K1; CK1; EHK; EHK1; EPPK; KRT1A; NEPPK
??[Similar Products]
NCBI Protein Information
keratin, type II cytoskeletal 1
UniProt Protein Name
Keratin, type II cytoskeletal 1
UniProt Synonym Protein Names
67 kDa cytokeratin; Cytokeratin-1; CK-1; Hair alpha protein; Keratin-1; K1; Type-II keratin Kb1
UniProt Gene Name
KRT1??[Similar Products]
UniProt Synonym Gene Names
KRTA; CK-1; K1??[Similar Products]
NCBI Summary for KRT1
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
UniProt Comments for KRT1
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.
Research Articles on KRT1
1. Results show that missense mutations exert dominant negative effects on the keratins K1/K10 protein structure by altering inter-chain interactions.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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