Product Name
methionine sulfoxide reductase B2 (MSRB2), Polyclonal Antibody
Full Product Name
Rabbit anti-human methionine sulfoxide reductase B2 polyclonal Antibody
Product Synonym Names
methionine sulfoxide reductase B2; MSRB2; CBS-1; CBS1; CGI-131; MGC26104; MSRB; PILB
Product Gene Name
anti-MSRB2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-163097 / sc-163100
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-MSRB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-MSRB2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for MSRB2. It may not necessarily be applicable to this product.
NCBI Accession #
AAI30381.1
[Other Products]
UniProt Secondary Accession #
Q17R44; Q4G1C7; Q9Y5W6[Other Products]
UniProt Related Accession #
Q9Y3D2[Other Products]
Molecular Weight
19,536 Da[Similar Products]
NCBI Official Full Name
Methionine sulfoxide reductase B2
NCBI Official Synonym Full Names
methionine sulfoxide reductase B2
NCBI Official Symbol
MSRB2??[Similar Products]
NCBI Official Synonym Symbols
CBS1; MSRB; PILB; CBS-1; CGI-131
??[Similar Products]
NCBI Protein Information
methionine-R-sulfoxide reductase B2, mitochondrial; pilin-like transcription factor
UniProt Protein Name
Methionine-R-sulfoxide reductase B2, mitochondrial
Protein Family
Methionine-R-sulfoxide reductase
UniProt Gene Name
MSRB2??[Similar Products]
UniProt Synonym Gene Names
CBS-1; MSRB; MsrB2??[Similar Products]
UniProt Entry Name
MSRB2_HUMAN
UniProt Comments for MSRB2
MSRB2: Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. Belongs to the MsrB Met sulfoxide reductase family.
Protein type: Mitochondrial; Oxidoreductase; EC 1.8.4.-; Transcription factor
Chromosomal Location of Human Ortholog: 10p12
Cellular Component: mitochondrion
Molecular Function: zinc ion binding; peptide-methionine (R)-S-oxide reductase activity; actin binding; transcription factor activity
Biological Process: protein repair; regulation of transcription, DNA-dependent; actin filament polymerization; response to oxidative stress
Research Articles on MSRB2
1. Data show that glutaredoxin acts as a reductant for methionine sulfoxide reductases A and B (MsrA and MsrB) with or without resolving cysteine.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
