Product Name
GBP1, Blocking Peptide
Full Product Name
GBP1 Peptide - middle region
Product Gene Name
GBP1 blocking peptide
[Similar Products]
GBP1 peptide (MBS3247064) is used for blocking the activity of GBP1 antibody (MBS3222391)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: YVTELTHRIR SKSSPDENEN EVEDSADFVS FFPDFVWTLR DFSLDLEADG
3D Structure
ModBase 3D Structure for P32455
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of GBP1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
GBP1 blocking peptide
This is a synthetic peptide designed for use in combination with anti- GBP1 Antibody, made
Target Description: Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.
Product Categories/Family for GBP1 blocking peptide
Peptide
NCBI/Uniprot data below describe general gene information for GBP1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002044.2
[Other Products]
NCBI GenBank Nucleotide #
NM_002053.2
[Other Products]
UniProt Primary Accession #
P32455
[Other Products]
UniProt Related Accession #
P32455[Other Products]
NCBI Official Full Name
guanylate-binding protein 1
NCBI Official Synonym Full Names
guanylate binding protein 1
NCBI Official Symbol
GBP1??[Similar Products]
NCBI Protein Information
guanylate-binding protein 1
UniProt Protein Name
Interferon-induced guanylate-binding protein 1
UniProt Synonym Protein Names
GTP-binding protein 1; GBP-1; HuGBP-1; Guanine nucleotide-binding protein 1
Protein Family
Guanylate-binding protein
UniProt Gene Name
GBP1??[Similar Products]
UniProt Synonym Gene Names
GBP-1; HuGBP-1??[Similar Products]
UniProt Entry Name
GBP1_HUMAN
NCBI Summary for GBP1
Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. [provided by RefSeq, Jul 2008]
UniProt Comments for GBP1
GBP1: a member of the family of large GTP-binding proteins (GBPs) that is inducible by interferon. Possesses a high GTP hydrolysis activity. GBPs are the most abundant cellular proteins expressed in response to interferon-gamma (IFN-gamma). IFN-gamma, tumor necrosis factor-alpha (TNF-alpha), and interleukin-1beta (IL-1beta) strongly induce the expression of GBP-1, -2, and -3.
Protein type: Vesicle; Cell adhesion; Hydrolase
Chromosomal Location of Human Ortholog: 1p22.2
Cellular Component: Golgi membrane; extracellular region; cytosol
Molecular Function: GTPase activity; identical protein binding; GTP binding
Biological Process: metabolic process; cytokine and chemokine mediated signaling pathway; defense response to virus
Research Articles on GBP1
1. we have found GBP1 was downregulated during osteogenic differentiation of hBM-MSCs. While knockdown of GBP1 promoted osteogenesis, overexpression of GBP1 suppressed osteogenesis of hBM-MSCs.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
