Full Product Name
GBP1 Antibody
Product Synonym Names
GBP-1; Guanine nucleotide-binding protein 1; Interferon-gamma inducible protein MAG-1; Interferon-induced guanylate-binding protein 1; MAG-1; MPA1
Product Gene Name
anti-GBP1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P32455
Specificity
GBP1 antibody detects endogenous levels of total GBP1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human GBP1.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-GBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-GBP1 antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-GBP1 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-GBP1 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:40000
Testing Data of anti-GBP1 antibody
Western Blot (WB) of anti-GBP1 antibody
Peptide-+ Western blot analysis of extracts from HUVEC cells, using GBP1 antibody. Immunofluorescence analysis of MCF-7 cells, using GBP1 antibody.
NCBI/Uniprot data below describe general gene information for GBP1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002044.2
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NCBI GenBank Nucleotide #
NM_002053.2
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UniProt Primary Accession #
P32455
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UniProt Secondary Accession #
Q5T8M1; D3DT26[Other Products]
UniProt Related Accession #
P32455[Other Products]
Molecular Weight
67,931 Da
NCBI Official Full Name
guanylate-binding protein 1
NCBI Official Synonym Full Names
guanylate binding protein 1
NCBI Official Symbol
GBP1??[Similar Products]
NCBI Protein Information
guanylate-binding protein 1
UniProt Protein Name
Guanylate-binding protein 1
UniProt Synonym Protein Names
GTP-binding protein 1; GBP-1; HuGBP-1; Guanine nucleotide-binding protein 1; Interferon-induced guanylate-binding protein 1
Protein Family
Guanylate-binding protein
UniProt Gene Name
GBP1??[Similar Products]
UniProt Synonym Gene Names
GBP-1; HuGBP-1??[Similar Products]
NCBI Summary for GBP1
Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. [provided by RefSeq, Jul 2008]
UniProt Comments for GBP1
Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
Product References and Citations for anti-GBP1 antibody
Cheng Y.-S.E., Mol. Cell. Biol. 11:4717-4725(1991). The MGC Project Team; Genome Res. 14:2121-2127(2004). Nantais D.E., J. Leukoc. Biol. 60:423-431(1996).
Research Articles on GBP1
1. These findings confirm the involvement of caspase-1 in non-classical secretion mechanisms and open novel perspectives for the extracellular function of secreted GBP-1.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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