Full Product Name
GBP1 Antibody - N-terminal region
Product Gene Name
anti-GBP1 antibody
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Antibody/Peptide Pairs
GBP1 peptide (MBS3247066) is used for blocking the activity of GBP1 antibody (MBS3222393)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: VVAIVGLYRT GKSYLMNKLA GKKKGFSLGS TVQSHTKGIW MWCVPHPKKP
3D Structure
ModBase 3D Structure for Q96PP8
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GBP1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-GBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GBP1 antibody
Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.
Product Categories/Family for anti-GBP1 antibody
Polyclonal; Signaling Intermediate; Cell Biology; Membrane & Traffic;
Applications Tested/Suitable for anti-GBP1 antibody
Western Blot (WB)
Western Blot (WB) of anti-GBP1 antibody
Host: Rabbit
Target Name: GBP1
Sample Tissue: Human MCF7 Whole Cell lysates
Antibody Dilution: 1ug/ml
NCBI/Uniprot data below describe general gene information for GBP1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002044.2
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NCBI GenBank Nucleotide #
NM_002053.2
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UniProt Primary Accession #
Q96PP8
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UniProt Related Accession #
P32455[Other Products]
NCBI Official Full Name
guanylate-binding protein 1
NCBI Official Synonym Full Names
guanylate binding protein 1
NCBI Official Symbol
GBP1??[Similar Products]
NCBI Protein Information
guanylate-binding protein 1
UniProt Protein Name
Guanylate-binding protein 5
UniProt Synonym Protein Names
GBP-TA antigen; GTP-binding protein 5; GBP-5; Guanine nucleotide-binding protein 5
Protein Family
Guanylate-binding protein
UniProt Gene Name
GBP5??[Similar Products]
UniProt Synonym Gene Names
GBP-5??[Similar Products]
UniProt Entry Name
GBP5_HUMAN
NCBI Summary for GBP1
Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. [provided by RefSeq, Jul 2008]
UniProt Comments for GBP1
GBP5: Stimulates the NLRP3 inflammasome assembly upon bacterial challenge. Belongs to the GBP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; Vesicle
Chromosomal Location of Human Ortholog: 1p22.2
Cellular Component: membrane; cytoplasmic vesicle
Molecular Function: GTPase activity; identical protein binding; GTP binding
Biological Process: metabolic process
Research Articles on GBP1
1. we have found GBP1 was downregulated during osteogenic differentiation of hBM-MSCs. While knockdown of GBP1 promoted osteogenesis, overexpression of GBP1 suppressed osteogenesis of hBM-MSCs.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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