Product Name
Espin (ESPN), ELISA Kit
Full Product Name
Human Espin (ESPN) ELISA Kit
Product Gene Name
ESPN elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for B1AK53
Preparation and Storage
Store at 2 to 8 degree C for 6 months.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of ESPN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for ESPN purchase
MBS161099 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Espin (ESPN) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ESPN. The ELISA analytical biochemical technique of the MBS161099 kit is based on ESPN antibody-ESPN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ESPN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ESPN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for ESPN. It may not necessarily be applicable to this product.
NCBI Accession #
NP_113663.2
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NCBI GenBank Nucleotide #
NM_031475.3
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UniProt Primary Accession #
B1AK53
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UniProt Secondary Accession #
Q6XYB2; Q9H0A2; Q9Y329[Other Products]
UniProt Related Accession #
B1AK53[Other Products]
Molecular Weight
31,636 Da
NCBI Official Full Name
espin
NCBI Official Synonym Full Names
espin
NCBI Official Symbol
ESPN??[Similar Products]
NCBI Official Synonym Symbols
DFNB36; LP2654
??[Similar Products]
NCBI Protein Information
espin
UniProt Protein Name
Espin
UniProt Synonym Protein Names
Autosomal recessive deafness type 36 protein; Ectoplasmic specialization protein
UniProt Gene Name
ESPN??[Similar Products]
UniProt Synonym Gene Names
DFNB36??[Similar Products]
NCBI Summary for ESPN
This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement. [provided by RefSeq, Nov 2009]
UniProt Comments for ESPN
Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimension, dynamics and signaling capacities of the actin filament-rich microvilli in the mechanosensory and chemosensory cells. Required for the assembly and stabilization of the stereociliary parallel actin bundles. Plays a crucial role in the formation and maintenance of inner ear hair cell stereocilia. Involved in the elongation of actin in stereocilia. In extrastriolar hair cells, required for targeting MYO3B to stereocilia tips, and for regulation of stereocilia diameter and staircase formation.
Research Articles on ESPN
1. A significant inverse correlation was observed between miR-612 and Espin protein expression in melanoma tissues.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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