Full Product Name
PIGW Antibody, Biotin conjugated
Product Synonym Names
Phosphatidylinositol-glycan biosynthesis class W protein; PIGW
Product Gene Name
anti-PIGW antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q7Z7B1
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Phosphatidylinositol-glycan biosynthesis class W protein (392-448AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-PIGW antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PIGW antibody
Required for the transport of GPI-anchored proteins to the plasma membrane (PubMed:24367057). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity).
Product Categories/Family for anti-PIGW antibody
Tags & Cell Markers
Applications Tested/Suitable for anti-PIGW antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for PIGW. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001333683.1
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NCBI GenBank Nucleotide #
NM_001346754.1
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UniProt Primary Accession #
Q7Z7B1
[Other Products]
UniProt Secondary Accession #
Q8N9G3[Other Products]
UniProt Related Accession #
Q7Z7B1[Other Products]
Molecular Weight
56,882 Da
NCBI Official Full Name
phosphatidylinositol-glycan biosynthesis class W protein
NCBI Official Synonym Full Names
phosphatidylinositol glycan anchor biosynthesis class W
NCBI Official Symbol
PIGW??[Similar Products]
NCBI Official Synonym Symbols
Gwt1; HPMRS5
??[Similar Products]
NCBI Protein Information
phosphatidylinositol-glycan biosynthesis class W protein
UniProt Protein Name
Phosphatidylinositol-glycan biosynthesis class W protein
Protein Family
Phosphatidylinositol-glycan biosynthesis class W protein
UniProt Gene Name
PIGW??[Similar Products]
UniProt Synonym Gene Names
PIG-W??[Similar Products]
NCBI Summary for PIGW
The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017]
UniProt Comments for PIGW
Required for the transport of GPI-anchored proteins to the plasma membrane (PubMed:24367057). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins ().
Precautions
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Disclaimer
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