Full Product Name
PIGV Antibody, HRP conjugated
Product Synonym Names
GPI mannosyltransferase 2; GPI mannosyltransferase II; GPI-MT-II; Phosphatidylinositol-glycan biosynthesis class V protein; PIG-V; PIGV
Product Gene Name
anti-PIGV antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9NUD9
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human GPI mannosyltransferase 2 protein (400-469AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-PIGV antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PIGV antibody
Alpha-1, 6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly.
Product Categories/Family for anti-PIGV antibody
Cancer; Metabolism; Signal transduction
Applications Tested/Suitable for anti-PIGV antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for PIGV. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001189483.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001202554.1
[Other Products]
UniProt Primary Accession #
Q9NUD9
[Other Products]
UniProt Secondary Accession #
Q5JYG7; Q5JYG8; Q5JYG9; Q9NX26; D3DPL2[Other Products]
UniProt Related Accession #
Q9NUD9[Other Products]
Molecular Weight
55,713 Da
NCBI Official Full Name
GPI mannosyltransferase 2
NCBI Official Synonym Full Names
phosphatidylinositol glycan anchor biosynthesis class V
NCBI Official Symbol
PIGV??[Similar Products]
NCBI Official Synonym Symbols
PIG-V; HPMRS1; GPI-MT-II
??[Similar Products]
NCBI Protein Information
GPI mannosyltransferase 2
UniProt Protein Name
GPI mannosyltransferase 2
UniProt Synonym Protein Names
GPI mannosyltransferase II; GPI-MT-II; Phosphatidylinositol-glycan biosynthesis class V protein; PIG-V
UniProt Gene Name
PIGV??[Similar Products]
UniProt Synonym Gene Names
GPI-MT-II; PIG-V??[Similar Products]
NCBI Summary for PIGV
This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia cognitive disability syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]
UniProt Comments for PIGV
Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly.
Research Articles on PIGV
1. Data indicate that mannosyltransferases PIGV mutations are the major cause of hyperphosphatasia-mental retardation syndrome (HPMRS) which displays a broad clinical variability regarding associated malformations and growth patterns.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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