Thymidine phosphorylase; TP; Gliostatin; Platelet-derived endothelial cell growth factor; PD-ECGF; TdRPase; TYMP; ECGF1; 2.4.2.4

For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C

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Small volumes of TYMP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9428591 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Thymidine phosphorylase (TYMP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TYMP. The ELISA analytical biochemical technique of the MBS9428591 kit is based on TYMP antibody-TYMP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TYMP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TYMP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

50,405 Da

thymidine phosphorylase

thymidine phosphorylase

Thymidine phosphorylase

ECGF1; TP; PD-ECGF??[Similar Products]

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

ECGF1: May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro. Homodimer. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.

Protein type: Cytokine; DNA replication; EC 2.4.2.4; Motility/polarity/chemotaxis; Nucleotide Metabolism - pyrimidine; Phosphorylase; Transferase; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 22q13.33

Cellular Component: cytosol

Molecular Function: phosphorylase activity; protein homodimerization activity; thymidine phosphorylase activity; transferase activity, transferring pentosyl groups

Biological Process: mitochondrial genome maintenance; pyrimidine nucleoside catabolic process; pyrimidine nucleoside metabolic process; pyrimidine nucleoside salvage; regulation of myelination; regulation of transmission of nerve impulse

Disease: Mitochondrial Dna Depletion Syndrome 1 (mngie Type)

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