Product Name
10 kDa heat shock protein (HSPE1), Polyclonal Antibody
Full Product Name
Rabbit anti-human 10 kDa heat shock protein, mitochondrial polyclonal Antibody, HRP conjugated
Product Gene Name
anti-HSPE1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P61604
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunogen
Recombinant human 10 kDa heat shock protein, mitochondrial protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21375 / sc-21373 / sc-20958
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-HSPE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HSPE1 antibody
Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
Applications Tested/Suitable for anti-HSPE1 antibody
ELISA (EIA)
Western Blot of anti-HSPE1 antibody
NCBI/Uniprot data below describe general gene information for HSPE1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002148.1
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NCBI GenBank Nucleotide #
NM_002157.2
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UniProt Primary Accession #
P61604
[Other Products]
UniProt Secondary Accession #
O95421; Q04984; Q53X54; Q9UDH0[Other Products]
UniProt Related Accession #
P61604[Other Products]
Molecular Weight
10,932 Da[Similar Products]
NCBI Official Full Name
10 kDa heat shock protein, mitochondrial
NCBI Official Synonym Full Names
heat shock protein family E (Hsp10) member 1
NCBI Official Symbol
HSPE1??[Similar Products]
NCBI Official Synonym Symbols
EPF; CPN10; GROES; HSP10
??[Similar Products]
NCBI Protein Information
10 kDa heat shock protein, mitochondrial
UniProt Protein Name
10 kDa heat shock protein, mitochondrial
UniProt Synonym Protein Names
10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor; EPF
Protein Family
10 kDa heat shock protein
UniProt Gene Name
HSPE1??[Similar Products]
UniProt Synonym Gene Names
Hsp10; CPN10; EPF??[Similar Products]
UniProt Entry Name
CH10_HUMAN
NCBI Summary for HSPE1
This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]
UniProt Comments for HSPE1
HSPE1: Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. Belongs to the GroES chaperonin family.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 2q33.1
Cellular Component: membrane; mitochondrial matrix; mitochondrion
Molecular Function: ATP binding; chaperone binding; protein binding; unfolded protein binding
Biological Process: caspase activation; osteoblast differentiation; protein folding; response to unfolded protein
Research Articles on HSPE1
1. Hsp10 has a role in nuclear localization and lung cells response to cigarette smoke
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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