Product Name
14-3-3 theta (YWHAQ), Blocking Peptide
Full Product Name
14-3-3 theta Blocking Peptide
Product Synonym Names
14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
Product Gene Name
YWHAQ blocking peptide
[Similar Products]
14-3-3 theta peptide (MBS8225566) is used for blocking the activity of 14-3-3 theta antibody (MBS8226226)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P27348
Species Reactivity
Human, Mouse, Rat, Bovine, Monkey
Form/Format
Lyophilized powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Directions for Use
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Other Notes
Small volumes of YWHAQ blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
YWHAQ blocking peptide
The peptide is used to block Anti-14-3-3 theta Antibody reactivity.
Applications Tested/Suitable for YWHAQ blocking peptide
Blocking (BL)
NCBI/Uniprot data below describe general gene information for YWHAQ. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006817.1
[Other Products]
NCBI GenBank Nucleotide #
NM_006826.3
[Other Products]
UniProt Primary Accession #
P27348
[Other Products]
UniProt Secondary Accession #
Q567U5; Q5TZU8; Q9UP48; D6W4Z5[Other Products]
UniProt Related Accession #
P27348[Other Products]
Molecular Weight
27,764 Da
NCBI Official Full Name
14-3-3 protein theta
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
NCBI Official Symbol
YWHAQ??[Similar Products]
NCBI Official Synonym Symbols
1C5; HS1; 14-3-3
??[Similar Products]
NCBI Protein Information
14-3-3 protein theta
UniProt Protein Name
14-3-3 protein theta
UniProt Synonym Protein Names
14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
Protein Family
14-3-3 protein
UniProt Gene Name
YWHAQ??[Similar Products]
UniProt Entry Name
1433T_HUMAN
NCBI Summary for YWHAQ
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
UniProt Comments for YWHAQ
14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 2p25.1
Cellular Component: cytoplasmic vesicle membrane; focal adhesion; membrane; cytoplasm; cytosol
Molecular Function: protein domain specific binding; protein binding; protein N-terminus binding
Biological Process: substantia nigra development; apoptosis; small GTPase mediated signal transduction; negative regulation of transcription, DNA-dependent; protein targeting
Research Articles on YWHAQ
1. 14-3-3S is an interesting protein biomarker with the potential to further improve the accuracy of differential diagnostic process of hepatocellular tumors.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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