Full Product Name
GBRR2 Polyclonal Antibody
Product Synonym Names
Gamma-aminobutyric acid receptor subunit rho-2; GABA(A) receptor subunit rho-2; GABA(C) receptor; GABRR2
Product Gene Name
anti-GBRR2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P28476
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-GBRR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GBRR2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GBRR2 antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for GBRR2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002034.3
[Other Products]
NCBI GenBank Nucleotide #
NM_002043.4
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UniProt Primary Accession #
P28476
[Other Products]
UniProt Secondary Accession #
Q9H153; A2BDE4[Other Products]
UniProt Related Accession #
P28476[Other Products]
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit rho-2
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor rho2 subunit
NCBI Official Symbol
GABRR2??[Similar Products]
NCBI Protein Information
gamma-aminobutyric acid receptor subunit rho-2
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit rho-2
UniProt Synonym Protein Names
GABA(A) receptor subunit rho-2; GABA(C) receptor
UniProt Gene Name
GABRR2??[Similar Products]
NCBI Summary for GBRR2
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA type A receptor complex. This gene exists on chromosome 6q next to the gene encoding the rho 1 subunit of the GABA type A receptor, in a region thought to be associated with susceptibility for psychiatric disorders and epilepsy. Polymorphisms in this gene may also be associated with alcohol dependence, and general cognitive ability. [provided by RefSeq, Apr 2016]
UniProt Comments for GBRR2
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission.
Research Articles on GBRR2
1. The genetic variant of GABRR2 gene contributes to the difference of individuals' general cognitive ability in a Chinese Han population.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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