Human Leukotriene-B (CYP4F3) ELISA kit; CPF3; CYP4F; LTB4H; cytochrome P-450; cytochrome P450; subfamily IVF; polypeptide 3 (leukotriene B4 omega hydroxylase) ; cytochrome P450-LTB-omega; leukotriene B4 omega hydroxylase; leukotriene-B4 20-mon; cytochrome P450; family 4; subfamily F; polypeptide 3

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of CYP4F3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9325560 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cytochrome P450, family 4, subfamily F, polypeptide 3 (CYP4F3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CYP4F3. The ELISA analytical biochemical technique of the MBS9325560 kit is based on CYP4F3 antibody-CYP4F3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CYP4F3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CYP4F3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

59,847 Da

cytochrome P450, family 4, subfamily F, polypeptide 3

leukotriene-B(4) omega-hydroxylase 2; leukotriene-B(4) omega-hydroxylase 2; CYPIVF3; cytochrome P-450; cytochrome P450 4F3; cytochrome P450-LTB-omega; leukotriene-B4 20-monooxygenase; leukotriene B4 omega hydroxylase; leukotriene-B(4) 20-monooxygenase 2; cytochrome P450, subfamily IVF, polypeptide 3 (leukotriene B4 omega hydroxylase)

Leukotriene-B(4) omega-hydroxylase 2

LTB4H??[Similar Products]

CP4F3_HUMAN

This gene, CYP4F3, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

CYP4F3: Cytochromes P450 are a group of heme-thiolate monooxygenases. This enzyme requires molecular oxygen and NADPH for the omega-hydroxylation of LTB4, a potent chemoattractant for polymorphonuclear leukocytes. Belongs to the cytochrome P450 family.

Protein type: Oxidoreductase; EC 1.14.13.30; Lipid Metabolism - arachidonic acid; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: leukotriene-B4 20-monooxygenase activity; iron ion binding; heme binding; monooxygenase activity

Biological Process: xenobiotic metabolic process; icosanoid metabolic process; arachidonic acid metabolic process; leukotriene metabolic process

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