Rat Gamma-aminobutyric acid receptor subunit rho-2 (GABRR2) ELISA kit; RP1-131H7.1; GABA-C receptor; rho-2 subunit; gamma-aminobutyric acid (GABA) receptor; rho 2

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of GABRR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9339766 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the gamma-aminobutyric acid (GABA) receptor, rho 2 (GABRR2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GABRR2. The ELISA analytical biochemical technique of the MBS9339766 kit is based on GABRR2 antibody-GABRR2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GABRR2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GABRR2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

54,296 Da

gamma-aminobutyric acid (GABA) A receptor, rho 2

gamma-aminobutyric acid receptor subunit rho-2; GABA(C) receptor; GABA(A) receptor subunit rho-2; gamma-aminobutyric acid A receptor, rho 2; gamma-aminobutyric acid (GABA) receptor, rho 2; gamma-aminobutyric acid (GABA-A) receptor subunit rho 2; gamma-aminobutyric acid (GABA-A) receptor, subunit rho 2; gamma-aminobutyric acid (GABA-C) receptor, subunit rho 2

Gamma-aminobutyric acid receptor subunit rho-2

GBRR2_RAT

may form bicuculline-insensitive GABA channels in the retina [RGD, Feb 2006]

GABRR2: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR2 sub-subfamily. 2 isoforms of the human protein are produced by alternative initiation.

Protein type: Transporter; Membrane protein, integral; Transporter, ion channel; Membrane protein, multi-pass

Cellular Component: postsynaptic membrane; cell junction

Molecular Function: protein domain specific binding; chloride channel activity; GABA-A receptor activity; inhibitory extracellular ligand-gated ion channel activity

Biological Process: eye photoreceptor cell development; visual perception; gamma-aminobutyric acid signaling pathway

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