Product Name
C-terminal-binding protein (CtBP), Recombinant Protein
Full Product Name
Recombinant Drosophila melanogaster C-terminal-binding protein (CtBP)
Product Gene Name
CtBP recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-476aa, full length protein
Sequence
MDKNLMMPKR SRIDVKGNFA NGPLQARPLV ALLDGRDCSI EMPILKDVAT VAFCDAQSTS EIHEKVLNEA VGALMWHTII LTKEDLEKFK ALRIIVRIGS GTDNIDVKAA GELGIAVCNV PGYGVEEVAD TTMCLILNLY RRTYWLANMV REGKKFTGPE QVREAAHGCA RIRGDTLGLV GLGRIGSAVA LRAKAFGFNV IFYDPYLPDG IDKSLGLTRV YTLQDLLFQS DCVSLHCTLN EHNHHLINEF TIKQMRPGAF LVNTARGGLV DDETLALALK QGRIRAAALD VHENEPYNVF QGALKDAPNL ICTPHAAFFS DASATELREM AATEIRRAIV GNIPDVLRNC VNKEYFMRTP PAAAAGGVAA AVYPEGALHH RAHSTTPHDG PHSTTNLGST VGGGPTTVAQ AAAAAVAAAA AAALLPSPVP SHLSPQVGGL PLGIVSSQSP LSAPDPNNHL SSSIKTEVKA ESTEAP
3D Structure
ModBase 3D Structure for O46036
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Drosophila melanogaster (Fruit fly)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CtBP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CtBP. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001014617.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001014617.2
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UniProt Primary Accession #
O46036
[Other Products]
UniProt Secondary Accession #
O61283; Q59DX5; Q95SQ8; Q9VG02[Other Products]
UniProt Related Accession #
O46036[Other Products]
Molecular Weight
42,252 Da
NCBI Official Full Name
C-terminal binding protein, isoform E
NCBI Official Synonym Full Names
C-terminal Binding Protein
NCBI Official Symbol
CtBP??[Similar Products]
NCBI Official Synonym Symbols
0256/16; 256/16; BcDNA:GH07572; CG7583; ctbp; CTBP; dCtBP; Dm-CtBP; DmelCG7583; EP(3)3528; G9; l(3)03463; l(3)03464; l(3)87De; l(3)87DE; l(3)G9; RE01030; RE61183
??[Similar Products]
NCBI Protein Information
CG7583 gene product from transcript CG7583-RE
UniProt Protein Name
C-terminal-binding protein
UniProt Synonym Protein Names
dCtBP
Protein Family
C-terminal-binding protein
UniProt Gene Name
CtBP??[Similar Products]
UniProt Synonym Gene Names
CtBP protein??[Similar Products]
UniProt Comments for CtBP
Corepressor targeting diverse transcription regulators. Hairy-interacting protein required for embryonic segmentation and hairy-mediated transcriptional repression.
Research Articles on CtBP
1. Here we provide evidence that although wild type CtBP negatively and dominantly influences Dpp signaling in fly presumptive wings, mutant CtBP unable to form dimer does not, indicating that dimerization is required for the repression role of CtBP in Dpp signaling in vivo.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
