Product Name
Laminin Gamma 3 (LAMC3), Recombinant Protein
Popular Item
Full Product Name
Recombinant Laminin Gamma 3 (LAMC3)
Product Gene Name
LAMC3 recombinant protein
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Matching Pairs
Unconjugated
Antibody: Laminin Gamma 3 (LAMC3) (MBS2001483)
Immunogen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
APC-CY7 Conjugated Antibody: Laminin Gamma 3 (LAMC3) (MBS2062951)
Immunogen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
PE Conjugated Antibody: Laminin Gamma 3 (LAMC3) (MBS2062953)
Immunogen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
APC Conjugated Antibody: Laminin Gamma 3 (LAMC3) (MBS2062955)
Immunogen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
Cy3 Conjugated Antibody: Laminin Gamma 3 (LAMC3) (MBS2062957)
Immunogen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
Cy3 Conjugated Antibody: Laminin Gamma 3 (LAMC3) (MBS2062958)
Immunogen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
FITC Conjugated Antibody: Laminin Gamma 3 (LAMC3) (MBS2062960)
Immunogen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
HRP Conjugated Antibody: Laminin Gamma 3 (LAMC3) (MBS2062962)
Immunogen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
Unconjugated Antibody: Laminin Gamma 3 (LAMC3) (MBS2085933)
Immunogen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
Biotin Conjugated Antibody: Laminin Gamma 3 (LAMC3) (MBS2091152)
Immunogen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
Antibody: Laminin Gamma 3 (LAMC3) (MBS2109403)
Antigen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
Antibody: Laminin Gamma 3 (LAMC3) (MBS2109404)
Antigen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
Antibody: Laminin Gamma 3 (LAMC3) (MBS2109405)
Antigen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
Antibody: Laminin Gamma 3 (LAMC3) (MBS2109406)
Antigen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
Antibody: Laminin Gamma 3 (LAMC3) (MBS2109407)
Antigen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Matching Pairs
Antibody: Laminin Gamma 3 (LAMC3) (MBS2109408)
Antigen: Laminin Gamma 3 (LAMC3) (MBS2009407)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS2009407 Technical Datasheet
Technical Datasheet PDF
Chromosome Location
Chromosome: 2; NC_000068.7 (31887281..31946535). Location: 2 B; 2
3D Structure
ModBase 3D Structure for Q9R0B6
Purity/Purification
> 97%
Form/Format
Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Concentration
Original Concentration: 200 Ug/mL (lot specific)
Organism Species
Mus musculus (Mouse)
Source
Prokaryotic expression
Subcellular Location
Membrane
Traits
Freeze-dried powder
Buffer formulation
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose
Predicted isoelectric point
9.9
Predicted Molecular Mass
19.6kDa
Accurate Molecular Mass
21kDa as determined by SDS-PAGE reducing conditions.
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8oC for one month.
Aliquot and store at -80oC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Other Notes
Small volumes of LAMC3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
LAMC3 recombinant protein
About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
Applications Tested/Suitable for LAMC3 recombinant protein
Positive Control, Immunogen, SDS-PAGE, WB.
(May be suitable for use in other assays to be determined by the end user.)
SDS-Page of LAMC3 recombinant protein
NCBI/Uniprot data below describe general gene information for LAMC3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_035966.2
[Other Products]
NCBI GenBank Nucleotide #
NM_011836.3
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UniProt Primary Accession #
Q9R0B6
[Other Products]
UniProt Secondary Accession #
Q4VAI3; Q9WTW6[Other Products]
UniProt Related Accession #
Q9R0B6[Other Products]
NCBI Official Full Name
laminin subunit gamma-3
NCBI Official Synonym Full Names
laminin gamma 3
NCBI Official Symbol
Lamc3??[Similar Products]
NCBI Official Synonym Symbols
AI562206; AW240805
??[Similar Products]
NCBI Protein Information
laminin subunit gamma-3; laminin-12 subunit gamma; laminin-14 subunit gamma; laminin-15 subunit gamma
UniProt Protein Name
Laminin subunit gamma-3
UniProt Synonym Protein Names
Laminin-12 subunit gamma; Laminin-14 subunit gamma; Laminin-15 subunit gamma
UniProt Gene Name
Lamc3??[Similar Products]
UniProt Entry Name
LAMC3_MOUSE
UniProt Comments for LAMC3
LAMC3: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Defects in LAMC3 are the cause of cortical malformations occipital (OCCM). OCCM is a disease in which affected individuals develop seizures, sometimes associated with transient visual changes. Brain MRI shows both pachygyria and polymicrogyria restricted to the lateral occipital lobes.
Protein type: Extracellular matrix; Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide
Cellular Component: proteinaceous extracellular matrix; extracellular region; basement membrane
Biological Process: cellular morphogenesis during differentiation; visual perception; retina development in camera-type eye; cell adhesion; astrocyte development
Research Articles on LAMC3
1. Deletion of Lamb2 and Lamc3 genes affects astrocyte migration and spatial patterning in the retina.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.