Product Name
LAMC3-Specific, Polyclonal Antibody
Full Product Name
LAMC3-Specific Antibody
Product Synonym Names
DKFZp434E202
Product Gene Name
anti-LAMC3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
Antigen affinity purification
Immunogen
Peptide of LAMC3-Specific
Calculated Molecular Weight: 1575aa; 171kd
Observed Molecular Weight: 173-200kd
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-LAMC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-LAMC3 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-LAMC3 antibody
WB: 1:500-1:5000
Testing Data of anti-LAMC3 antibody
NCBI/Uniprot data below describe general gene information for LAMC3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_035966.2
[Other Products]
NCBI GenBank Nucleotide #
NM_011836.3
[Other Products]
UniProt Secondary Accession #
Q4VAI3; Q9WTW6[Other Products]
UniProt Related Accession #
Q9R0B6[Other Products]
Molecular Weight
172,322 Da
NCBI Official Full Name
laminin subunit gamma-3
NCBI Official Synonym Full Names
laminin gamma 3
NCBI Official Symbol
Lamc3??[Similar Products]
NCBI Official Synonym Symbols
AI562206; AW240805
??[Similar Products]
NCBI Protein Information
laminin subunit gamma-3; laminin-12 subunit gamma; laminin-14 subunit gamma; laminin-15 subunit gamma
UniProt Protein Name
Laminin subunit gamma-3
UniProt Synonym Protein Names
Laminin-12 subunit gamma; Laminin-14 subunit gamma; Laminin-15 subunit gamma
UniProt Gene Name
Lamc3??[Similar Products]
UniProt Entry Name
LAMC3_MOUSE
UniProt Comments for LAMC3
LAMC3: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Defects in LAMC3 are the cause of cortical malformations occipital (OCCM). OCCM is a disease in which affected individuals develop seizures, sometimes associated with transient visual changes. Brain MRI shows both pachygyria and polymicrogyria restricted to the lateral occipital lobes.
Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Extracellular matrix; Secreted
Cellular Component: proteinaceous extracellular matrix; extracellular region; basement membrane
Biological Process: cellular morphogenesis during differentiation; visual perception; retina development in camera-type eye; cell adhesion; astrocyte development
Research Articles on LAMC3
1. Deletion of Lamb2 and Lamc3 genes affects astrocyte migration and spatial patterning in the retina.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
