Full Product Name
CPS1 Antibody, Biotin conjugated
Product Synonym Names
Carbamoyl-phosphate synthase [ammonia], mitochondrial; Carbamoyl-phosphate synthetase I; CPSase I; CPS1
Product Gene Name
anti-CPS1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P31327
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Carbamoyl-phosphate synthase [ammonia], mitochondrial protein (1361-1500AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-CPS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CPS1 antibody
Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.
Product Categories/Family for anti-CPS1 antibody
Cancer; Tags & Cell Markers; Metabolism; Signal transduction
Applications Tested/Suitable for anti-CPS1 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for CPS1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001116105.1
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NCBI GenBank Nucleotide #
NM_001122633.2
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UniProt Primary Accession #
P31327
[Other Products]
UniProt Secondary Accession #
O43774; Q53TL5; Q59HF8; Q7Z5I5; B7Z818; J3KQL0[Other Products]
UniProt Related Accession #
P31327[Other Products]
Molecular Weight
165,650 Da
NCBI Official Full Name
carbamoyl-phosphate synthase
NCBI Official Synonym Full Names
carbamoyl-phosphate synthase 1
NCBI Official Symbol
CPS1??[Similar Products]
NCBI Official Synonym Symbols
PHN; CPSASE1
??[Similar Products]
NCBI Protein Information
carbamoyl-phosphate synthase [ammonia], mitochondrial
UniProt Protein Name
Carbamoyl-phosphate synthase [ammonia], mitochondrial
UniProt Synonym Protein Names
Carbamoyl-phosphate synthetase I; CPSase I
Protein Family
Carboxypeptidase
UniProt Gene Name
CPS1??[Similar Products]
UniProt Synonym Gene Names
CPSase I??[Similar Products]
NCBI Summary for CPS1
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.[provided by RefSeq, May 2010]
UniProt Comments for CPS1
Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.
Research Articles on CPS1
1. CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
