Homeobox protein Hox-D10; Homeobox protein Hox-45; Homeobox protein Hox-53; Hoxd10; Hox-45; Hoxd-10

For Research Use Only. Not for use in diagnostic procedures.

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Small volumes of Hoxd10 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

38,328 Da

homeobox D10

homeobox protein Hox-D10

Homeobox protein Hox-D10

Hox-4.5; Hoxd-10??[Similar Products]

HXD10_MOUSE

HOXD10: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Defects in HOXD10 are a cause of congenital vertical talus (CVT); also known as rocker-bottom foot deformity or congenital convex pes valgus. CVT is a dislocation of the talonavicular joint, with rigid dorsal dislocation of the navicular over the neck of the talus. This condition is usually associated with multiple other congenital deformities and only rarely is an isolated deformity. Belongs to the Abd-B homeobox family.

Protein type: DNA-binding

Molecular Function: chromatin binding; DNA binding; protein binding; transcription factor activity

Biological Process: ***** locomotory behavior; anterior/posterior pattern formation; embryonic limb morphogenesis; embryonic skeletal morphogenesis; forelimb morphogenesis; hindlimb morphogenesis; neuromuscular process; peripheral nervous system neuron development; positive regulation of transcription from RNA polymerase II promoter; proximal/distal pattern formation; regulation of gene expression; single fertilization; skeletal development; skeletal muscle development; spinal cord motor neuron cell fate specification

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