Full Product Name
HoxD10 Antibody
Product Gene Name
anti-HoxD10 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P28358
Other Notes
Small volumes of anti-HoxD10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Western Blot (WB) of anti-HoxD10 antibody
Western blot analysis HoxD10 using K562 whole cell lysates
NCBI/Uniprot data below describe general gene information for HoxD10. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002139.2
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NCBI GenBank Nucleotide #
NM_002148.3
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UniProt Primary Accession #
P28358
[Other Products]
UniProt Secondary Accession #
Q6NT10[Other Products]
UniProt Related Accession #
P28358[Other Products]
Molecular Weight
38,411 Da
NCBI Official Full Name
homeobox protein Hox-D10
NCBI Official Synonym Full Names
homeobox D10
NCBI Official Symbol
HOXD10??[Similar Products]
NCBI Official Synonym Symbols
HOX4; HOX4D; HOX4E; Hox-4.4
??[Similar Products]
NCBI Protein Information
homeobox protein Hox-D10
UniProt Protein Name
Homeobox protein Hox-D10
UniProt Synonym Protein Names
Homeobox protein Hox-4D; Homeobox protein Hox-4E
Protein Family
Homeobox protein
UniProt Gene Name
HOXD10??[Similar Products]
UniProt Synonym Gene Names
HOX4D; HOX4E??[Similar Products]
NCBI Summary for HoxD10
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
UniProt Comments for HoxD10
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Research Articles on HoxD10
1. Knock down of the dickkopf WNT signaling pathway inhibitor 2 (DKK2) resulted in a significant suppression of HOXD10, HOXD11 and HOXD13 while over-expression of DKK2 and stimulation with factors of the WNT signaling pathway.
Precautions
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Disclaimer
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