Full Product Name
ZP2 Antibody
Product Gene Name
anti-ZP2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q05996
Other Notes
Small volumes of anti-ZP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Western Blot (WB) of anti-ZP2 antibody
Western blot analysis ZP2 using COLO205 whole cell lysates
NCBI/Uniprot data below describe general gene information for ZP2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001277033.1
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NCBI GenBank Nucleotide #
NM_001290104.1
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UniProt Primary Accession #
Q05996
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UniProt Secondary Accession #
Q4VAN9; Q4VAP0; Q4VAP1; B2R7J2[Other Products]
UniProt Related Accession #
Q05996[Other Products]
Molecular Weight
81,300 Da
NCBI Official Full Name
zona pellucida sperm-binding protein 2 isoform 2 preproprotein
NCBI Official Synonym Full Names
zona pellucida glycoprotein 2
NCBI Official Symbol
ZP2??[Similar Products]
NCBI Official Synonym Symbols
ZPA; Zp-2
??[Similar Products]
NCBI Protein Information
zona pellucida sperm-binding protein 2
UniProt Protein Name
Zona pellucida sperm-binding protein 2
UniProt Synonym Protein Names
Zona pellucida glycoprotein 2; Zp-2
Protein Family
Zona pellucida sperm-binding protein
UniProt Gene Name
ZP2??[Similar Products]
UniProt Synonym Gene Names
ZPA; Zp-2??[Similar Products]
NCBI Summary for ZP2
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed of three glycoproteins with various functions during fertilization and preimplantation development. The glycosylated mature peptide is one of the structural components of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. Female mice lacking this gene do not form a stable zona matrix and are sterile. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
UniProt Comments for ZP2
The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor.
Research Articles on ZP2
1. Mutations in ZP2 and ZP3 have dosage effects which can cause female infertility in humans.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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