Full Product Name
HOXD10 Antibody
Product Synonym Names
homeobox d10; hox-4.4; hox4; hox4d; hox4e; hoxd10
Product Gene Name
anti-HOXD10 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P28358
Species Reactivity
Human, Mouse
Specificity
HOXD10 antibody detects endogenous levels of total HOXD10 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human HOXD10.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-HOXD10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-HOXD10 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-HOXD10 antibody
WB: 1:500~1:1000
ELISA: 1:40000
Western Blot (WB) of anti-HOXD10 antibody
Western blot analysis of extracts from K562 cells and RAW264.7 cells, using HOXD10 antibody.
NCBI/Uniprot data below describe general gene information for HOXD10. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002139.2
[Other Products]
NCBI GenBank Nucleotide #
NM_002148.3
[Other Products]
UniProt Primary Accession #
P28358
[Other Products]
UniProt Secondary Accession #
Q6NT10[Other Products]
UniProt Related Accession #
P28358[Other Products]
Molecular Weight
38,411 Da
NCBI Official Full Name
homeobox protein Hox-D10
NCBI Official Synonym Full Names
homeobox D10
NCBI Official Symbol
HOXD10??[Similar Products]
NCBI Official Synonym Symbols
HOX4; HOX4D; HOX4E; Hox-4.4
??[Similar Products]
NCBI Protein Information
homeobox protein Hox-D10
UniProt Protein Name
Homeobox protein Hox-D10
UniProt Synonym Protein Names
Homeobox protein Hox-4D; Homeobox protein Hox-4E
Protein Family
Homeobox protein
UniProt Gene Name
HOXD10??[Similar Products]
UniProt Synonym Gene Names
HOX4D; HOX4E??[Similar Products]
NCBI Summary for HOXD10
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
UniProt Comments for HOXD10
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Product References and Citations for anti-HOXD10 antibody
Zappavigna V., EMBO J. 10:4177-4187(1991). Redline R.W., Genomics 13:425-430(1992). Acampora D., Nucleic Acids Res. 17:10385-10402(1989).
Research Articles on HOXD10
1. Knock down of the dickkopf WNT signaling pathway inhibitor 2 (DKK2) resulted in a significant suppression of HOXD10, HOXD11 and HOXD13 while over-expression of DKK2 and stimulation with factors of the WNT signaling pathway.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
