Product Name
Zona pellucida sperm-binding protein 2 (Zp2), Recombinant Protein
Full Product Name
Recombinant Mouse Zona pellucida sperm-binding protein 2 (Zp2)
Product Synonym Names
Zona pellucida sperm-binding protein 2; Zona pellucida glycoprotein 2; Zp-2; Zona pellucida protein ACleaved into the following chain:; 1. Processed zona pellucida sperm-binding protein 2
Product Gene Name
Zp2 recombinant protein
[Similar Products]
Product Synonym Gene Name
Zp2; Zp-2; Zpa[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
35-683
Sequence
VSLPQS ENPAFPGTLI CDKDEVRIEF SSRFDMEKWN PSVVDTLGSE ILNCTYALDL ERFVLKFPYE TCTIKVVGGY QVNIRVGDTT TDVRYKDDMY HFFCPAIQAE THEISEIVVC RRDLISFSFP QLFSRLADEN QNVSEMGWIV KIGNGTRAHI LPLKDAIVQG FNLLIDSQKV TLHVPANATG IVHYVQESSY LYTVQLELLF STTGQKIVFS SHAICAPDLS VACNATHMTL TIPEFPGKLE SVDFGQWSIP EDQWHANGID KEATNGLRLN FRKSLLKTKP SEKCPFYQFY LSSLKLTFYF QGNMLSTVID PECHCESPVS IDELCAQDGF MDFEVYSHQT KPALNLDTLL VGNSSCQPIF KVQSVGLARF HIPLNGCGTR QKFEGDKVIY ENEIHALWEN PPSNIVFRNS EFRMTVRCYY IRDSMLLNAH VKGHPSPEAF VKPGPLVLVL QTYPDQSYQR PYRKDEYPLV RYLRQPIYME VKVLSRNDPN IKLVLDDCWA TSSEDPASAP QWQIVMDGCE YELDNYRTTF HPAGSSAAHS GHYQRFDVKT FAFVSEARGL SSLIYFHCSA LICNQVSLDS PLCSVTCPAS LRSKREANKE DTMTVSLPGP ILLLSDVSSS KGVDPSSSEI TKDIIAKDIA SKT
3D Structure
ModBase 3D Structure for P20239
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mus musculus (Mouse)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Zp2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Zp2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_035905.1
[Other Products]
NCBI GenBank Nucleotide #
NM_011775.6
[Other Products]
UniProt Primary Accession #
P20239
[Other Products]
UniProt Related Accession #
P20239[Other Products]
Molecular Weight
80,210 Da
NCBI Official Full Name
zona pellucida sperm-binding protein 2
NCBI Official Synonym Full Names
zona pellucida glycoprotein 2
NCBI Official Symbol
Zp2??[Similar Products]
NCBI Official Synonym Symbols
Zp-2
??[Similar Products]
NCBI Protein Information
zona pellucida sperm-binding protein 2; zona pellucida protein A; zona pellucida glycoprotein ZP2
UniProt Protein Name
Zona pellucida sperm-binding protein 2
UniProt Synonym Protein Names
Zona pellucida glycoprotein 2; Zp-2; Zona pellucida protein ACleaved into the following chain:Processed zona pellucida sperm-binding protein 2
Protein Family
Zona pellucida sperm-binding protein
UniProt Gene Name
Zp2??[Similar Products]
UniProt Synonym Gene Names
Zp-2; Zpa; Zp-2??[Similar Products]
UniProt Entry Name
ZP2_MOUSE
UniProt Comments for Zp2
ZP2: The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor. Belongs to the ZP domain family. ZPA subfamily.
Protein type: Membrane protein, integral
Cellular Component: multivesicular body; Golgi apparatus; extracellular matrix; proteinaceous extracellular matrix; membrane; endoplasmic reticulum; plasma membrane; extracellular region; integral to membrane; secretory granule
Molecular Function: acrosin binding; protein binding
Biological Process: intracellular protein transport; binding of sperm to zona pellucida; single fertilization; manganese ion transport
Research Articles on Zp2
1. ZP2(51-149) sperm-binding domain is necessary for mouse gamete recognition and penetration through the zona pellucida.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
