Product Name
Galpha olf, Polyclonal Antibody
Full Product Name
Galpha olf Polyclonal Antibody
Product Gene Name
anti-Galpha olf antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P38405
Other Notes
Small volumes of anti-Galpha olf antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Galpha olf. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001135811.1
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NCBI GenBank Nucleotide #
NM_001142339.2
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UniProt Primary Accession #
P38405
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UniProt Secondary Accession #
Q86XU3; B7ZA26[Other Products]
UniProt Related Accession #
P38405[Other Products]
Molecular Weight
20,522 Da
NCBI Official Full Name
guanine nucleotide-binding protein G(olf) subunit alpha isoform 2
NCBI Official Synonym Full Names
G protein subunit alpha L
NCBI Official Symbol
GNAL??[Similar Products]
NCBI Official Synonym Symbols
DYT25
??[Similar Products]
NCBI Protein Information
guanine nucleotide-binding protein G(olf) subunit alpha
UniProt Protein Name
Guanine nucleotide-binding protein G(olf) subunit alpha
UniProt Synonym Protein Names
Adenylate cyclase-stimulating G alpha protein, olfactory type
UniProt Gene Name
GNAL??[Similar Products]
NCBI Summary for Galpha olf
This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
UniProt Comments for Galpha olf
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
Research Articles on Galpha olf
1. GNAL mutation may represent one of the rare causative genetic factors of isolated laryngeal dystonia.
Precautions
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Disclaimer
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